并发急性中耳炎的假单胞菌性迷路炎:病例报告

Ghada Kharrat, Sana Ferchichi, Zahra Jouini
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摘要

背景:细菌性迷路炎很少见。假单胞菌感染更是罕见。在此,我们将介绍一例假单胞菌性迷路炎病例,并讨论该病的诊断、影像学检查的价值、治疗和预后。病例报告:一名 18 岁女性,因突发性左侧听力下降、旋转性眩晕、呕吐和耳鸣就诊,病程持续 24 小时。十天前,她出现了急性中耳炎的症状。耳内镜检查发现鼓膜穿孔,并伴有脓性耳屎。前庭检查显示有协调的外周前庭综合征。音调听力图显示左侧感音性耳聋。颞部计算机断层扫描显示左侧中耳翳。磁共振成像(MRI)排除了胆脂瘤性中耳炎,建设性干扰稳态(CISS)序列显示迷宫强化。耳道样本培养分离出铜绿假单胞菌。她最初接受了头孢他啶联合万古霉素的概率性静脉抗生素治疗 17 天,然后,我们改用了适应性抗生素。她总共接受了 25 天的抗生素治疗和 14 天的皮质类固醇治疗。她还接受了前庭康复治疗和高压氧治疗。头晕症状有所缓解,但耳聋仍然存在。结论在使用抗生素治疗的时代,迷路炎越来越罕见。在这种情况下,铜绿假单胞菌是一种特殊的病菌。磁共振成像是阳性诊断和鉴别诊断不可或缺的工具。
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Pseudomonas Labyrinthitis Complicating Acute Otitis Media: Case Report.

Background: Bacterial labyrinthitis has been rarely described. Pseudomonas incrimination is even exceptional. Herein, we present a case of pseudomonas labyrinthitis and discuss diagnosis, value of imaging, treatment and prognosis of this entity. Case Report: A 18-year-old female presented with left sudden hearing loss, rotatory vertigo, vomiting, and tinnitus evolving for 24 hours. Ten days earlier, she presented symptoms of acute media otitis. Otoendoscopic examination revealed a tympanic perforation with purulent otorrhea. Vestibular examination revealed a harmonious peripheric vestibular syndrome. A tonal audiogram showed a left perceptive deafness. A temporal computed tomography scan showed left opacity of the middle ear. Magnetic resonance imaging (MRI) excluded cholesteatomatous otitis, and constructive interference steady state (CISS) sequence revealed intense labyrinthine enhancement. Otorrhea sample culture isolated Pseudomonas aeruginosa. She initially received probabilistic intravenous antibiotherapy associating cefotaxime to vancomycin for 17 days, then, we switched to adapt to the antibiogram. She had a total of 25 days of antibiotic therapy and 14 days of corticosteroid treatment. She also benefited of vestibular rehabilitation and hyperbaric oxygenotherapy. The dizziness subsided, but the deafness persisted. Conclusion: Labyrinthitis is increasingly rare in the era of antibiotic therapy. P. aeruginosa is an exceptional germ in this context. MRI is an indispensable tool for the positive and the differential diagnosis.

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