重新审视酒精与攻击之间的联系:酒精消费模式的影响。

IF 3.9 2区 医学 Q1 PSYCHIATRY Drug and alcohol dependence Pub Date : 2024-11-08 DOI:10.1016/j.drugalcdep.2024.112496
Maayan Nagar , Sharon Rabinovitz
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引用次数: 0

摘要

实验室研究多次报道了酒精与攻击行为之间的联系,但许多研究依赖于单剂量给药方法,忽略了酒精消费模式的变化。本研究采用一种双盲、安慰剂对照的累积饮酒给药方法,在实验室环境中模拟在酒吧经常观察到的自然饮酒行为,研究酒精对攻击行为的影响。这项研究还率先探讨了酒精消费模式(轻度或重度)如何调节精确的呼气酒精浓度(BrAC)水平与极端攻击行为之间的关系。75 名轻度(38 人)和重度(37 人)饮酒者被随机分配到酒精(33 人)或安慰剂(42 人)条件下。参与者连续饮用四杯酒。每次饮酒二十分钟后完成泰勒攻击范式。采用多层次模型分析了精确 BrAC 的影响,并考虑了人体内的变异性。酒精对攻击行为的影响呈剂量依赖性;随着酒精水平的升高,攻击行为也随之升高(P3 元理论(Finkel,2014 年))。研究结果强调了调查急性和慢性饮酒对行为的相互影响的重要性,对传统的危险饮酒分类阈值提出了挑战。研究还讨论了对未来研究、立法者和政策制定者的启示。
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Revisiting the alcohol-aggression link: The impact of alcohol consumption patterns
Laboratory studies have repeatedly reported a link between alcohol and aggression, yet many rely on single-dose administration methods and overlook variations in alcohol consumption patterns. The present study investigates the effects of alcohol on aggressive behavior using a double-blind, placebo-controlled cumulative drinking administration approach that mirrors the natural drinking behaviors often observed in pubs within a laboratory setting. This study also pioneers the examination of how alcohol consumption patterns (light or heavy) moderate the relationship between precise Breath Alcohol Concentration (BrAC) levels and extreme aggressive behavior. Seventy-five individuals who drink alcohol lightly (N=38) and heavily (N=37) were randomly assigned to alcohol (N=33) or placebo (N=42) conditions. Participants drank four drinks successively. Taylor's aggression paradigm was completed twenty minutes after each drink. Multilevel modeling was applied to analyze the effects of precise BrAC and account for within-person variability. Alcohol showed a dose-dependent effect on aggression; as alcohol levels rose, so did aggression (p<.001). Alcohol consumption pattern moderated the effect of cumulative BrAC on aggression, such that the effect was more substantial for as compared with individuals who drink lightly (p=.03). The current study highlights the moderating role of alcohol consumption pattern in the association between precise BrAC levels and extreme aggression, offering insights into individual differences in susceptibility to alcohol-induced aggression, and supporting the I3 meta-theory (Finkel, 2014). The Findings underscore the importance of investigating the interplay between acute and chronic alcohol use on behavior, challenging conventional thresholds for hazardous drinking classification. Implications for future studies, legislators, and policymakers are discussed.
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来源期刊
Drug and alcohol dependence
Drug and alcohol dependence 医学-精神病学
CiteScore
7.40
自引率
7.10%
发文量
409
审稿时长
41 days
期刊介绍: Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.
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