Juyoung Park, Heling Tong, Yixin Kang, Hongyu Miao, Lifeng Lin, Rina S Fox, Ilknur Telkes, Geraldine Martorella, Hyochol Ahn
{"title":"经颅直流电刺激后膝关节骨关节炎有反应者与无反应者的比较。","authors":"Juyoung Park, Heling Tong, Yixin Kang, Hongyu Miao, Lifeng Lin, Rina S Fox, Ilknur Telkes, Geraldine Martorella, Hyochol Ahn","doi":"10.1080/17581869.2024.2429943","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.</p><p><strong>Patients and methods/materials: </strong>Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.</p><p><strong>Results: </strong>Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders (<i>p</i> < .001). Participants with higher BMI (<i>p</i> = .02) and weight (<i>p</i> = .005) were more likely to respond, while no significant sociodemographic differences were found.</p><p><strong>Conclusions: </strong>Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.</p><p><strong>Clinical trial registration: </strong>www.clinicaltrials.gov identifier is NCT04016272.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"507-518"},"PeriodicalIF":1.4000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of responders and nonresponders with knee osteoarthritis after transcranial direct current stimulation.\",\"authors\":\"Juyoung Park, Heling Tong, Yixin Kang, Hongyu Miao, Lifeng Lin, Rina S Fox, Ilknur Telkes, Geraldine Martorella, Hyochol Ahn\",\"doi\":\"10.1080/17581869.2024.2429943\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.</p><p><strong>Patients and methods/materials: </strong>Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.</p><p><strong>Results: </strong>Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders (<i>p</i> < .001). Participants with higher BMI (<i>p</i> = .02) and weight (<i>p</i> = .005) were more likely to respond, while no significant sociodemographic differences were found.</p><p><strong>Conclusions: </strong>Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.</p><p><strong>Clinical trial registration: </strong>www.clinicaltrials.gov identifier is NCT04016272.</p>\",\"PeriodicalId\":20000,\"journal\":{\"name\":\"Pain management\",\"volume\":\" \",\"pages\":\"507-518\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pain management\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/17581869.2024.2429943\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/16 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pain management","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17581869.2024.2429943","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/16 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Comparison of responders and nonresponders with knee osteoarthritis after transcranial direct current stimulation.
Aim: The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.
Patients and methods/materials: Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.
Results: Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders (p < .001). Participants with higher BMI (p = .02) and weight (p = .005) were more likely to respond, while no significant sociodemographic differences were found.
Conclusions: Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.
Clinical trial registration: www.clinicaltrials.gov identifier is NCT04016272.
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