{"title":"在一名有神经系统表现的患者中同时诊断出克氏锥虫和艾滋病病毒:病例报告。","authors":"Emmanuel Molina Solano , Mauricio Mora Díaz , Stephanie Montoya Madriz , Mauricio Lizano Calvo , Lissette Retana Moreira","doi":"10.1016/j.bjid.2024.104478","DOIUrl":null,"url":null,"abstract":"<div><div>American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite <em>Trypanosoma cruzi,</em> characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of <em>T. cruzi</em> in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.</div></div>","PeriodicalId":56327,"journal":{"name":"Brazilian Journal of Infectious Diseases","volume":"28 6","pages":"Article 104478"},"PeriodicalIF":3.0000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report\",\"authors\":\"Emmanuel Molina Solano , Mauricio Mora Díaz , Stephanie Montoya Madriz , Mauricio Lizano Calvo , Lissette Retana Moreira\",\"doi\":\"10.1016/j.bjid.2024.104478\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite <em>Trypanosoma cruzi,</em> characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of <em>T. cruzi</em> in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.</div></div>\",\"PeriodicalId\":56327,\"journal\":{\"name\":\"Brazilian Journal of Infectious Diseases\",\"volume\":\"28 6\",\"pages\":\"Article 104478\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Brazilian Journal of Infectious Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S141386702400761X\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S141386702400761X","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report
American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.
期刊介绍:
The Brazilian Journal of Infectious Diseases is the official publication of the Brazilian Society of Infectious Diseases (SBI). It aims to publish relevant articles in the broadest sense on all aspects of microbiology, infectious diseases and immune response to infectious agents.
The BJID is a bimonthly publication and one of the most influential journals in its field in Brazil and Latin America with a high impact factor, since its inception it has garnered a growing share of the publishing market.