在一名有神经系统表现的患者中同时诊断出克氏锥虫和艾滋病病毒:病例报告。

IF 3 4区 医学 Q2 INFECTIOUS DISEASES Brazilian Journal of Infectious Diseases Pub Date : 2024-11-01 DOI:10.1016/j.bjid.2024.104478
Emmanuel Molina Solano , Mauricio Mora Díaz , Stephanie Montoya Madriz , Mauricio Lizano Calvo , Lissette Retana Moreira
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引用次数: 0

摘要

美洲锥虫病或恰加斯病是一种由原生动物克鲁斯锥虫引起的病媒传染病,分为急性期和慢性期;免疫抑制可导致再活化。在本病例报告中,我们证实一名有神经系统表现的患者体内存在克鲁兹锥虫。为此,我们采用了一系列技术,包括脑脊液直接检查、Giemsa 染色、样本培养、血清学和分子技术。患者接受了为期 6 个月的硝呋太尔制霉素治疗,并开始接受抗逆转录病毒治疗,因为同时还进行了艾滋病毒诊断,结果显示没有后遗症或不良反应。对患者的健康状况进行了 42 个月的随访。
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Concomitant diagnosis of Trypanosoma cruzi and HIV in a patient with neurologic manifestations: A case report
American trypanosomiasis or Chagas disease is a vector-borne infection caused by the protozoan parasite Trypanosoma cruzi, characterized by acute and chronic phases; reactivations due to immunosuppression can occur. In this case report, we confirm the presence of trypomastigotes of T. cruzi in a patient with neurologic manifestations. For this purpose, a battery of techniques, including direct examination of cerebrospinal fluid, Giemsa stains, sample cultures, serology and molecular techniques were employed. The patient was treated with nifurtimox for 6 months and started antiretroviral therapy as the concomitant diagnosis of HIV was also performed, showing no sequelae nor adverse effects. A follow-up of the patient´s health status was performed for 42 months.
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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
925
审稿时长
41 days
期刊介绍: The Brazilian Journal of Infectious Diseases is the official publication of the Brazilian Society of Infectious Diseases (SBI). It aims to publish relevant articles in the broadest sense on all aspects of microbiology, infectious diseases and immune response to infectious agents. The BJID is a bimonthly publication and one of the most influential journals in its field in Brazil and Latin America with a high impact factor, since its inception it has garnered a growing share of the publishing market.
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