全球癌症治疗的差距:缩小高收入国家和低收入国家在药物可负担性和可获得性方面的差距。

IF 6.1 2区 医学 Q1 ONCOLOGY Cancer Pub Date : 2024-11-18 DOI:10.1002/cncr.35590
Arafat H Tfayli, Laura N El-Halabi, Fadlo R Khuri
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引用次数: 0

摘要

背景:尽管在癌症领域取得了显著进展,但癌症仍然是医疗保健系统面临的重大挑战。这些进步具有重大的财务影响,对低收入国家的影响尤为严重。这篇综述文章旨在探讨药物开发的现状,评估药物在不同收入国家的可用性,并提出潜在的解决方案,以解决癌症新疗法获取不平等的问题:方法:于 2023 年 10 月 2 日在 MEDLINE 和 PubMed 上进行搜索,并于 2023 年 12 月 14 日更新,仅限于英文文章:预计全球癌症病例将会增加,尤其是在低收入国家,因为这些国家中与癌症相关的死亡人数预计最多。尽管癌症治疗方法的批准率有所上升,但其高昂的费用和负担能力严重阻碍了癌症治疗方法的普及。关键癌症药物成本的差异受到地理位置和采购关系的影响。解决药物分配不公的潜在方案包括共享生产机密、实行价格歧视、国际资助、改善初级卫生保健措施以及实施具有成本效益的筛查方法:结论:癌症的预防、筛查和治疗应成为全球优先事项,各国在获得治疗方面的差异应降到最低。
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Global disparities in cancer care: Bridging the gap in affordability and access to medications between high and low-income countries.

Background: Cancer remains a significant challenge for health care systems, despite notable progress in the field. These advancements have significant financial implications that disproportionately affect low-income countries. This review article aims to explore the present state of drug development, assessing the availability of drugs in different income countries, and proposing potential solutions to address the inequality in access to new cancer treatments.

Methods: A search was conducted on MEDLINE and PubMed on October 2, 2023 and updated on December 14, 2023, limited to English language articles.

Results: There is a projected rise in cancer cases worldwide, particularly in low-income countries where most cancer-related deaths are expected. Although the approval rate of cancer treatments has risen, their excessive cost and lack of affordability pose significant barriers to widespread access. Disparities in the costs of crucial cancer medications are influenced by geographic location and procurement connections. Potential solutions to address the inequity in drug distribution include sharing production secrets, implementing price discrimination, international funding, improved primary health care measures, and the implementation of cost-effective screening methods.

Conclusion: Preventing, screening for, and treating cancer should be a global priority with minimal differences in access to therapy among various countries.

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来源期刊
Cancer
Cancer 医学-肿瘤学
CiteScore
13.10
自引率
3.20%
发文量
480
审稿时长
2-3 weeks
期刊介绍: The CANCER site is a full-text, electronic implementation of CANCER, an Interdisciplinary International Journal of the American Cancer Society, and CANCER CYTOPATHOLOGY, a Journal of the American Cancer Society. CANCER publishes interdisciplinary oncologic information according to, but not limited to, the following disease sites and disciplines: blood/bone marrow; breast disease; endocrine disorders; epidemiology; gastrointestinal tract; genitourinary disease; gynecologic oncology; head and neck disease; hepatobiliary tract; integrated medicine; lung disease; medical oncology; neuro-oncology; pathology radiation oncology; translational research
期刊最新文献
A systematic review and meta-analysis of patient-relevant outcomes in comprehensive cancer centers versus noncomprehensive cancer centers. American Society of Clinical Oncology guideline update on palliative care for patients with cancer: Addressing the reality gap. Embrace with caution: The limitations of generative artificial intelligence in responding to patient health care queries. Expression of Concern. Global disparities in cancer care: Bridging the gap in affordability and access to medications between high and low-income countries.
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