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引用次数: 0
摘要
在真核细胞中，AMP-活化蛋白激酶（AMPK）通过关闭 ATP 消耗（合成代谢）途径和开启 ATP 生成（分解代谢）途径，在应对营养限制方面发挥着核心作用。在过去的 30 多年里，大量的研究为我们提供了有关 AMPK 的调节和作用的丰富知识。尽管如此，关于 AMPK 仍有许多知识需要学习，而且该领域仍然非常活跃，世界各地的许多研究小组都在继续探索 AMPK 的新作用，为我们深入了解其生物功能提供依据。本系列综述受到最近在苏格兰（2022 年）和澳大利亚（2023 年）举行的以 AMPK 为主题的会议的启发，并借鉴了在这些会议上发表的一些研究成果。
A special issue of Essays in Biochemistry on AMPK and AMPK-related kinases.
In eukaryotic cells, AMP-activated protein kinase (AMPK) plays a central role in responding to nutrient limitation by switching-off ATP-consuming (anabolic) pathways and switching-on ATP generating (catabolic) pathways. Over the last 30 years or so, a considerable body of research has been carried out that has provided us with a wealth of knowledge regarding the regulation and role of AMPK. Despite this, there is still much to learn about AMPK and the field remains highly active, with many groups around the world continuing to explore new roles for AMPK, providing insight into its biological function. This review series was inspired by recent AMPK-focused meetings in Scotland (2022) and Australia (2023) and draws on some of the research presented at those meetings.
期刊介绍：
Essays in Biochemistry publishes short, digestible reviews from experts highlighting recent key topics in biochemistry and the molecular biosciences. Written to be accessible for those not yet immersed in the subject, each article is an up-to-date, self-contained summary of the topic.
Bridging the gap between the latest research and established textbooks, Essays in Biochemistry will tell you what you need to know to begin exploring the field, as each article includes the top take-home messages as summary points.
Each issue of the journal is guest edited by a key opinion leader in the area, and whether you are continuing your studies or moving into a new research area, the Journal gives a complete picture in one place.
Essays in Biochemistry is proud to publish Understanding Biochemistry, an essential online resource for post-16 students, teachers and undergraduates. Providing up-to-date overviews of key concepts in biochemistry and the molecular biosciences, the Understanding Biochemistry issues of Essays in Biochemistry are published annually in October.
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