联合习惯逆转疗法和接纳与承诺疗法治疗妥瑞症抽搐症：关于疗效和反应持续时间的试点研究。

IF 2.6 4区医学 Q2 CLINICAL NEUROLOGY Movement Disorders Clinical Practice Pub Date : 2024-11-18 DOI:10.1002/mdc3.14260

Jennifer Eisenhauer, Alison Buckland, Stuart Watson, Rick Stell

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引用次数: 0

摘要

背景：很少有研究对基于正念的疗法治疗抽动秽语综合征的有效性和持续时间进行研究。本研究将习惯逆转疗法（HRT）与接受和承诺疗法（ACT）相结合：评估习惯逆转疗法+接纳与承诺疗法在降低成人妥瑞症患者抽搐严重程度方面的疗效和反应持续时间：方法：在基线、干预后、6 个月和 12 个月的随访中，使用耶鲁全球抽搐严重程度量表（YGTSS）和视频评估对抽搐严重程度进行评估。干预包括每周八次、每次 1 小时的疗程：混合效应回归显示，治疗后抽搐严重程度明显降低（b = -10.36，P = 0.002），并在 6 个月（b = -8.19，P = 0.012）和 12 个月（b = -8.82，P = 0.009）时保持不变。视频评估证实了这些结果：HRT+ACT方案有效降低了抽搐的严重程度，其疗效可持续12个月。这些结果支持进一步进行试验，比较 HRT + ACT 与单独使用 HRT 的效果。

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Combined Habit Reversal Therapy and Acceptance and Commitment Therapy for Treatment of Tics in Tourette Syndrome: A Pilot Study of Effectiveness and Response Duration.

Background: Few studies have examined the effectiveness and duration of mindfulness-based therapies for tics in Tourette's syndrome. This study combined habit reversal therapy (HRT) with acceptance and commitment therapy (ACT).

Objectives: To evaluate the efficacy and response duration of HRT + ACT in reducing tic severity in adults with Tourette's Syndrome.

Methods: Tic severity was assessed at baseline, post-intervention, and at 6- and 12-month follow-ups using the Yale Global Tic Severity Scale (YGTSS) and video assessments. The intervention included eight weekly 1-h sessions.

Results: Mixed-effects regression showed significant reductions in tic severity post-treatment (b = -10.36, P = 0.002), maintained at 6 months (b = -8.19, P = 0.012) and 12 months (b = -8.82, P = 0.009). Video assessments confirmed these findings.

Conclusion: The HRT + ACT protocol effectively reduced tic severity, with benefits lasting 12 months. These results support further trials to compare HRT + ACT with HRT alone.

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来源期刊

Movement Disorders Clinical Practice CLINICAL NEUROLOGY-

CiteScore

4.00

自引率

7.50%

发文量

218

期刊介绍： Movement Disorders Clinical Practice- is an online-only journal committed to publishing high quality peer reviewed articles related to clinical aspects of movement disorders which broadly include phenomenology (interesting case/case series/rarities), investigative (for e.g- genetics, imaging), translational (phenotype-genotype or other) and treatment aspects (clinical guidelines, diagnostic and treatment algorithms)