{"title":"2018-2023年中国云南省海鸥空肠弯曲杆菌中新出现的R类唾液寡糖有可能诱发格林-巴利综合征。","authors":"Xiaoli Chen, Yixin Gu, Hairui Wang, Guilan Zhou, Xin Zhang, Chang Liu, Zhujun Shao, Jianzhong Zhang, Maojun Zhang","doi":"10.46234/ccdcw2024.237","DOIUrl":null,"url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Lipooligosaccharides from <i>Campylobacter jejuni</i> (<i>C. jejuni</i>) have a mimicry antigen structure with gangliosides, which explains the mechanism by which <i>C. jejuni</i> caused Guillain-Barré syndrome (GBS).</p><p><strong>What is added by this report?: </strong>All 12 <i>C. jejuni</i> strains with class R LOSs and specific serotypes were isolated from seagulls in south China. These emerging <i>C. jejuni</i> strains had ganglioside-mimicry antigen structures and possessed a high potential for triggering GBS.</p><p><strong>What are the implications for public health practice?: </strong>Sialylated lipooligosaccharides (LOS) class R with GBS-associated serotypes isolated from seagulls highlight the risk of induced GBS around coastal or lakeside areas.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"6 45","pages":"1177-1182"},"PeriodicalIF":4.3000,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561365/pdf/","citationCount":"0","resultStr":"{\"title\":\"Emerging Sialylated Class R Lipooligosaccharides in <i>Campylobacter jejuni</i> from Seagulls Has the Potential to Trigger Guillain-Barré Syndrome - Yunnan Province, China, 2018-2023.\",\"authors\":\"Xiaoli Chen, Yixin Gu, Hairui Wang, Guilan Zhou, Xin Zhang, Chang Liu, Zhujun Shao, Jianzhong Zhang, Maojun Zhang\",\"doi\":\"10.46234/ccdcw2024.237\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>What is already known about this topic?: </strong>Lipooligosaccharides from <i>Campylobacter jejuni</i> (<i>C. jejuni</i>) have a mimicry antigen structure with gangliosides, which explains the mechanism by which <i>C. jejuni</i> caused Guillain-Barré syndrome (GBS).</p><p><strong>What is added by this report?: </strong>All 12 <i>C. jejuni</i> strains with class R LOSs and specific serotypes were isolated from seagulls in south China. These emerging <i>C. jejuni</i> strains had ganglioside-mimicry antigen structures and possessed a high potential for triggering GBS.</p><p><strong>What are the implications for public health practice?: </strong>Sialylated lipooligosaccharides (LOS) class R with GBS-associated serotypes isolated from seagulls highlight the risk of induced GBS around coastal or lakeside areas.</p>\",\"PeriodicalId\":69039,\"journal\":{\"name\":\"中国疾病预防控制中心周报\",\"volume\":\"6 45\",\"pages\":\"1177-1182\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2024-11-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561365/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国疾病预防控制中心周报\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.46234/ccdcw2024.237\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国疾病预防控制中心周报","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.46234/ccdcw2024.237","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
关于这一主题的已知信息空肠弯曲菌（C. jejuni）的脂寡糖与神经节苷脂具有拟态抗原结构，这解释了空肠弯曲菌导致吉兰-巴雷综合征（GBS）的机制：所有 12 株具有 R 类 LOS 和特定血清型的空肠大肠杆菌都是从中国南方的海鸥中分离出来的。这些新出现的空肠大肠杆菌菌株具有神经节苷脂模拟抗原结构，诱发GBS的可能性很高。对公共卫生实践有何意义？ 从海鸥中分离到的R类ialylated lipooligosaccharides（LOS）和GBS相关血清型突显了沿海或湖滨地区诱发GBS的风险。
Emerging Sialylated Class R Lipooligosaccharides in Campylobacter jejuni from Seagulls Has the Potential to Trigger Guillain-Barré Syndrome - Yunnan Province, China, 2018-2023.
What is already known about this topic?: Lipooligosaccharides from Campylobacter jejuni (C. jejuni) have a mimicry antigen structure with gangliosides, which explains the mechanism by which C. jejuni caused Guillain-Barré syndrome (GBS).
What is added by this report?: All 12 C. jejuni strains with class R LOSs and specific serotypes were isolated from seagulls in south China. These emerging C. jejuni strains had ganglioside-mimicry antigen structures and possessed a high potential for triggering GBS.
What are the implications for public health practice?: Sialylated lipooligosaccharides (LOS) class R with GBS-associated serotypes isolated from seagulls highlight the risk of induced GBS around coastal or lakeside areas.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
