Wei Yang, Dan Zhou, Hui Peng, Huilin Jiang, Weifeng Chen
{"title":"败血症患者体温与 28 天死亡率之间的关系：回顾性观察研究","authors":"Wei Yang, Dan Zhou, Hui Peng, Huilin Jiang, Weifeng Chen","doi":"10.1016/j.medine.2024.08.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</p><p><strong>Design: </strong>Retrospective cohort analysis.</p><p><strong>Setting: </strong>208 ICUs in the United States.</p><p><strong>Patients or participants: </strong>Sepsis patients from 2014-2015 eICU Collaborative Research Database.</p><p><strong>Interventions: </strong>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</p><p><strong>Main variables of interest: </strong>Body temperature, 28-day inpatient mortality.</p><p><strong>Results: </strong>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70-0.80, p < 0.0001).</p><p><strong>Conclusions: </strong>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</p>","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study.\",\"authors\":\"Wei Yang, Dan Zhou, Hui Peng, Huilin Jiang, Weifeng Chen\",\"doi\":\"10.1016/j.medine.2024.08.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</p><p><strong>Design: </strong>Retrospective cohort analysis.</p><p><strong>Setting: </strong>208 ICUs in the United States.</p><p><strong>Patients or participants: </strong>Sepsis patients from 2014-2015 eICU Collaborative Research Database.</p><p><strong>Interventions: </strong>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</p><p><strong>Main variables of interest: </strong>Body temperature, 28-day inpatient mortality.</p><p><strong>Results: </strong>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70-0.80, p < 0.0001).</p><p><strong>Conclusions: </strong>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</p>\",\"PeriodicalId\":94139,\"journal\":{\"name\":\"Medicina intensiva\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicina intensiva\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.medine.2024.08.004\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina intensiva","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.medine.2024.08.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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