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Congenital absence of the circumflex coronary artery. 先天性冠状动脉圆周缺失。
Pub Date : 2025-03-03 DOI: 10.1016/j.medine.2025.502152
Antonio Padilla-Serrano, Carmen de la Cueva Coca, Antonio Cárdenas Cruz
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引用次数: 0
Dual therapy with remdesivir plus extended nirmatrelvir/ritonavir in immunocompromised and critically ill patient with suspected persistent COVID-19 infection: Case report 对疑似持续感染 COVID-19 的免疫力低下危重病人使用雷米地韦加延长的尼马瑞韦/利托那韦双重疗法:病例报告。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.11.005
Arturo Gámiz Rejano , Teresa López-Viñau , Cristina López Martín , Samira Marín Moreno , Isabel Machuca , Jorge Rodríguez-Gómez
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引用次数: 0
Septic shock due to Chromobacterium violaceum after a trip to Azores Islands. A fatal and unusual pathogen 亚速尔群岛之行后,因感染Chromobacterium violaceum而引发败血症性休克。这是一种致命的不寻常病原体。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.11.002
Beatriz Morillo Muela, Alejandro José Martín Damián, Adela Fernández Galilea, Álvaro López López
{"title":"Septic shock due to Chromobacterium violaceum after a trip to Azores Islands. A fatal and unusual pathogen","authors":"Beatriz Morillo Muela, Alejandro José Martín Damián, Adela Fernández Galilea, Álvaro López López","doi":"10.1016/j.medine.2024.11.002","DOIUrl":"10.1016/j.medine.2024.11.002","url":null,"abstract":"","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":"49 3","pages":"Pages 183-184"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient safety, what does clinical simulation and teaching innovation contribute? 患者安全,临床模拟和教学创新有何贡献?
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.04.012
María Jesús Broch Porcar, Álvaro Castellanos-Ortega
Clinical simulation in Intensive Care Medicine is a crucial tool to strengthen patient safety. It focuses on the complexity of the Intensive Care Unit, where challenging clinical situations require rapid decision making and the use of invasive techniques that can increase the risk of errors and compromise safety. Clinical simulation, by mimicking clinical contexts, is presented as essential for developing technical and non-technical skills and enhancing teamwork in a safe environment, without harm to the patient. in situ simulation is a valuable approach to practice in realistic environments and to address latent security threats. Other simulation methods as virtual reality and tele-simulation are gaining more and more acceptance. Herein, we provide current data on the clinical utility of clinical simulation related to improved safety in the practice of techniques and procedures, as well as improvements of teamwork performance and outcomes. Finally, we propose the needs for future research.
重症监护医学中的临床模拟是加强患者安全的重要工具。它重点关注重症监护病房的复杂性,在这种具有挑战性的临床情况下,需要快速做出决策并使用侵入性技术,这可能会增加出错的风险并危及安全。临床模拟通过模拟临床环境,对发展技术和非技术技能以及在安全环境中加强团队合作至关重要,同时不会对病人造成伤害。虚拟现实和远程模拟等其他模拟方法正被越来越多的人所接受。在此,我们将提供有关临床模拟的临床实用性的最新数据,这些数据涉及提高技术和程序实践的安全性,以及改善团队合作绩效和成果。最后,我们提出了未来研究的需求。
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引用次数: 0
Clinical efficacy of oXiris-continuous hemofiltration adsorption in septic shock patients: A retrospective analysis 脓毒性休克患者使用 oXiris 连续血液滤过吸附的临床疗效:回顾性分析
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.09.012
Yuxin Yang, Qionglan Dong, Jianpeng Su, Hongjun Xiao, Dan Zan, Jinfeng Chen, Xue Chen, Fan Wei, Cheng Zeng, Yanyan Yong

Objective

This study aimed to assess the clinical impact of oXiris-continuous hemofiltration adsorption on patients with septic shock and their prognosis.

Design

A retrospective study.

Participants

Septic shock patients.

Interventions

The oXiris group underwent hemofiltration adsorption using oXiris hemofilters and septic shock standard treatment, while the control group received septic shock standard treatment.

Main variables of interest

The changes in inflammatory indicators and short-term mortality rate were evaluated. Propensity score matching (PSM) was conducted based on the 1:2 ratio between the oXiris and control groups to account for any baseline data differences.

Results

Results showed that after 24 h, 48 h, and 72 h of treatment, PCT, IL-6, and hs-CRP levels in the oXiris group were significantly lower than those in the control group (P < 0.05). However, there were no significant differences in norepinephrine equivalents and organ function status (APACHE II score, SOFA score, Lac) between the two groups at the same time points. The 72-h mortality rate (21.88% vs. 34.04%) and the 7-day mortality rate (28.12% vs. 44.68%) were lower in the oXiris group compared to the control group, but not statistically significant. The 28-day mortality rate did not show a significant difference between the two groups (53.19% vs. 56.25%).

Conclusions

oXiris continuous hemofiltration adsorption technology may reduce the levels of inflammatory factors in patients with septic shock; however, it does not appear to enhance organ function or improve the 28-day mortality rate in these patients.
研究目的本研究旨在评估奥希瑞斯-连续性血液滤过吸附对脓毒性休克患者的临床影响及其预后:参与者:脓毒性休克患者脓毒性休克患者:oXiris组使用oXiris血液过滤器进行血液过滤吸附,并接受脓毒性休克标准治疗,对照组接受脓毒性休克标准治疗:主要研究变量:评估炎症指标和短期死亡率的变化。根据 oXiris 组和对照组 1:2 的比例进行倾向得分匹配(PSM),以考虑任何基线数据差异:结果显示,治疗 24 小时、48 小时和 72 小时后,oXiris 组的 PCT、IL-6 和 hs-CRP 水平显著低于对照组(P 结论:oXiris 连续血液过滤吸附技术可降低脓毒性休克患者的炎症因子水平,但似乎并不能增强这些患者的器官功能或改善其 28 天死亡率。
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引用次数: 0
Fistula from subclavian artery to right internal jugular vein secondary to firearm injury 枪伤导致锁骨下动脉至右颈内静脉瘘。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.07.011
Antonio Padilla-Serrano , Ala Eddine Daoudi El Boukhrissi , Genaro López Milena
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引用次数: 0
Guided reversal of dabigatran in massive hemorrhagic shock 大面积失血性休克患者在达比加群引导下逆转治疗:病例报告。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.10.002
Manuel Fernández Caro , Manuel Casado Méndez , Francisco Javier Rodríguez Martorell , Antonio Manuel Puppo Moreno
{"title":"Guided reversal of dabigatran in massive hemorrhagic shock","authors":"Manuel Fernández Caro ,&nbsp;Manuel Casado Méndez ,&nbsp;Francisco Javier Rodríguez Martorell ,&nbsp;Antonio Manuel Puppo Moreno","doi":"10.1016/j.medine.2024.10.002","DOIUrl":"10.1016/j.medine.2024.10.002","url":null,"abstract":"","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":"49 3","pages":"Pages 181-182"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Removal of giant bronchial clot with cryoadhesion probe 用低温粘附探针移除巨大的支气管血栓。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.07.012
Mónica García Simón, Cristina Sanchís Piqueras, Georgia García Fernández
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引用次数: 0
Current perspectives on the use of artificial intelligence in critical patient safety 人工智能在危重病人安全中的应用现状。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.04.002
Jesús Abelardo Barea Mendoza , Marcos Valiente Fernandez , Alex Pardo Fernandez , Josep Gómez Álvarez
Intensive Care Units (ICUs) have undergone enhancements in patient safety, and artificial intelligence (AI) emerges as a disruptive technology offering novel opportunities. While the published evidence is limited and presents methodological issues, certain areas show promise, such as decision support systems, detection of adverse events, and prescription error identification. The application of AI in safety may pursue predictive or diagnostic objectives. Implementing AI-based systems necessitates procedures to ensure secure assistance, addressing challenges including trust in such systems, biases, data quality, scalability, and ethical and confidentiality considerations.
The development and application of AI demand thorough testing, encompassing retrospective data assessments, real-time validation with prospective cohorts, and efficacy demonstration in clinical trials. Algorithmic transparency and explainability are essential, with active involvement of clinical professionals being crucial in the implementation process.
重症监护病房(ICU)的患者安全得到了加强,而人工智能(AI)作为一种颠覆性技术的出现则提供了新的机遇。虽然已发表的证据有限,且存在方法论问题,但某些领域仍大有可为,如决策支持系统、不良事件检测和处方错误识别。人工智能在安全领域的应用可以实现预测或诊断目标。要实施基于人工智能的系统,就必须制定确保安全协助的程序,应对包括对此类系统的信任、偏差、数据质量、可扩展性以及道德和保密考虑在内的挑战。人工智能的开发和应用需要全面的测试,包括回顾性数据评估、前瞻性队列的实时验证以及临床试验中的疗效展示。算法的透明度和可解释性至关重要,临床专业人员的积极参与对实施过程至关重要。
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引用次数: 0
Correlation and concordance of HACOR and IROX scales in patients with COVID-19 pneumonia who received non-invasive ventilation in two intensive care units 在两个重症监护病房接受无创通气治疗的 COVID-19 肺炎患者的 HACOR 和 IROX 量表的相关性和一致性。
Pub Date : 2025-03-01 DOI: 10.1016/j.medine.2024.11.007
Alberto Belenguer-Muncharaz , Irina Hermosilla-Semikina , Francisco Bernal-Julián , Héctor Hernández-Garcés , Lluís Tormo-Rodriguez , Estefanía Granero-Gasamans
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引用次数: 0
期刊
Medicina intensiva
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