Yu-Rui Xie , Shan-Shan Ling , Yan-Xi Li , Mei-Ru Wang , Hai-Yang Liu
{"title":"从云南巴黎根茎中提取的两种新的酚醛苷类化合物","authors":"Yu-Rui Xie , Shan-Shan Ling , Yan-Xi Li , Mei-Ru Wang , Hai-Yang Liu","doi":"10.1016/j.phytol.2024.11.007","DOIUrl":null,"url":null,"abstract":"<div><div>Phytochemical investigation on the rhizomes of <em>Paris yunnanensis</em> led to the isolation of two undescribed phenolic glycosides (<strong>1</strong> and <strong>2</strong>), and three known analogues (<strong>3</strong>-<strong>5</strong>). Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, MS, and UV. Among them, compounds <strong>1</strong> and <strong>2</strong> have a rare 4-<em>O</em>-<em>β</em>-D-apiofuranosyl group. The DPPH radical scavenging activities of the isolated compounds were evaluated and compound <strong>3</strong> exhibited moderate DPPH radical scavenging activity with an EC<sub>50</sub> value of 72.6 μM, while Vitamin C was used as the positive control (EC<sub>50</sub> = 24.6 μM).</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"65 ","pages":"Pages 15-18"},"PeriodicalIF":1.3000,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Two new phenolic glycosides from the rhizomes of Paris yunnanensis\",\"authors\":\"Yu-Rui Xie , Shan-Shan Ling , Yan-Xi Li , Mei-Ru Wang , Hai-Yang Liu\",\"doi\":\"10.1016/j.phytol.2024.11.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Phytochemical investigation on the rhizomes of <em>Paris yunnanensis</em> led to the isolation of two undescribed phenolic glycosides (<strong>1</strong> and <strong>2</strong>), and three known analogues (<strong>3</strong>-<strong>5</strong>). Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, MS, and UV. Among them, compounds <strong>1</strong> and <strong>2</strong> have a rare 4-<em>O</em>-<em>β</em>-D-apiofuranosyl group. The DPPH radical scavenging activities of the isolated compounds were evaluated and compound <strong>3</strong> exhibited moderate DPPH radical scavenging activity with an EC<sub>50</sub> value of 72.6 μM, while Vitamin C was used as the positive control (EC<sub>50</sub> = 24.6 μM).</div></div>\",\"PeriodicalId\":20408,\"journal\":{\"name\":\"Phytochemistry Letters\",\"volume\":\"65 \",\"pages\":\"Pages 15-18\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-11-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phytochemistry Letters\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1874390024001538\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phytochemistry Letters","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1874390024001538","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Two new phenolic glycosides from the rhizomes of Paris yunnanensis
Phytochemical investigation on the rhizomes of Paris yunnanensis led to the isolation of two undescribed phenolic glycosides (1 and 2), and three known analogues (3-5). Their structures were determined by extensive spectroscopic analysis, including 1D and 2D NMR, MS, and UV. Among them, compounds 1 and 2 have a rare 4-O-β-D-apiofuranosyl group. The DPPH radical scavenging activities of the isolated compounds were evaluated and compound 3 exhibited moderate DPPH radical scavenging activity with an EC50 value of 72.6 μM, while Vitamin C was used as the positive control (EC50 = 24.6 μM).
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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