返回:香叶木素通过减少氧化应激和心肌凋亡对新生大鼠心肌缺血损伤具有心脏保护作用

IF 2.9 4区 医学 Q2 Medicine Clinical and Experimental Pharmacology and Physiology Pub Date : 2024-11-18 DOI:10.1111/1440-1681.70009
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引用次数: 0

摘要

撤回:G. Mo, Y. He, X. Zhang, X. Lei and Q. Luo, "Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decrease Oxidative Stress and Myocardial Apoptosis," Clinical and Experimental Pharmacology and Physiology 47, no. 10 (2020): 1713-1722, https://doi.org/10.1111/1440-1681.13309.上述文章于 2020 年 3 月 27 日在线发表于 Wiley Online Library (wileyonlinelibrary.com),经作者、期刊主编杨洋和 John Wiley & Sons Australia, Ltd. 协议,已被撤回。论文发表后,作者向期刊通报了影响其研究结果有效性和完整性的重大问题。他们承认,氧化应激标记物和心肌细胞凋亡水平的几个数据点与原始实验室记录不一致。经过我们的分析,发现了更多值得关注的问题。特别是图 1D 中 Western 印迹中显示的肌动蛋白条带和图 5A 中的 P65、p-P65 和 p-AKT 条带在其他文章中被发现是重复的。作者没有回应我们对这些额外问题的评论请求。编辑认为这篇文章的结果和结论无效。
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RETRACTION: Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis

RETRACTION: G. Mo, Y. He, X. Zhang, X. Lei and Q. Luo, “ Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis,” Clinical and Experimental Pharmacology and Physiology 47, no. 10 (2020): 17131722, https://doi.org/10.1111/1440-1681.13309.

The above article, published online on 27 March 2020 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Yang Yang; and John Wiley & Sons Australia, Ltd. Following publication, the authors notified the journal of significant issues affecting the validity and integrity of their findings. They acknowledged that several data points for oxidative stress markers and myocardial apoptosis levels were inconsistent with the original laboratory records. Following our own analysis, further concerns were identified. Specifically, the actin bands shown in the western blot in Figure 1D and the P65, p-P65, and p-AKT bands in Figure 5A were found to be duplicated in other articles. The authors did not respond to our requests for comments on these additional issues. The editors have deemed the results and conclusions of this article invalid.

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来源期刊
CiteScore
6.20
自引率
0.00%
发文量
128
审稿时长
6 months
期刊介绍: Clinical and Experimental Pharmacology and Physiology is an international journal founded in 1974 by Mike Rand, Austin Doyle, John Coghlan and Paul Korner. Our focus is new frontiers in physiology and pharmacology, emphasizing the translation of basic research to clinical practice. We publish original articles, invited reviews and our exciting, cutting-edge Frontiers-in-Research series’.
期刊最新文献
Biochemical Investigation of the Association of Apolipoprotein E Gene Allele Variations with Insulin Resistance and Amyloid-β Aggregation in Cardiovascular Disease TLR4 Inhibitor TAK-242 Protected Henoch–Schonlein Purpura Nephritis in Rats by Regulating Inflammatory Response and Immune Competence via NF- κB/NLRP3 Signalling Issue Information Disability status investigation and risk prediction model for middle-aged and older adults in Anhui Province: A derivation and validation study RETRACTION: Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis
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