治疗癌症患者内脏动脉损伤的临床结果和 Viabahn 支架移植物闭塞的风险因素。

Yuji Koretsune, Hiroki Higashihara, Satoshi Toyoda, Miho Yamakawa, Koji Mikami, Noboru Maeda, Hiroshi Yukimoto, Keisuke Nagai, Masahisa Nakamura, Noriyuki Tomiyama
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摘要

目的:本研究旨在评估在内脏动脉损伤中放置Viabahn支架移植物的临床效果,并确定与支架移植物闭塞相关的风险因素:这项多中心、回顾性研究纳入了2017年12月至2022年11月期间为26名接受Viabahn支架移植物置入术的患者实施的29例手术。我们使用对比增强计算机断层扫描评估了技术和临床成功率、围手术期并发症以及支架移植物的通畅性。我们进行了单变量分析,以研究与 Viabahn 支架移植物闭塞相关的风险因素:技术成功率为 96.6%(29 例中有 28 例),临床成功率为 86.2%(29 例中有 25 例)。围手术期并发症发生率为 17.2%(29 例中有 5 例),包括 4 例轻度不良事件和 1 例患者死亡。1、3、6、12 和 24 个月的支架移植物通畅率分别为 85%、84.2%、77.8%、66.7% 和 50%。单变量分析表明,缺乏抗血小板药物(P = .00074)与SG过大≥20%(P = .047)之间存在显著相关性:这项试验证明了 Viabahn 支架移植物置入治疗内脏动脉损伤的安全性和有效性,且通畅率很高。此外,该研究还发现,缺乏抗血小板治疗和 Viabahn 过大≥ 20% 是内脏动脉损伤中 Viabahn 支架移植物阻塞的重要风险因素。
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Clinical Outcomes and Risk Factors for Viabahn Stent Graft Occlusion in the Treatment of Visceral Arterial Injuries in Cancer Patients.

Purpose: This study aimed to evaluate the clinical outcomes of placing Viabahn stent grafts in visceral arterial injuries and identify the risk factors associated with stent graft occlusion.

Material and method: This multicenter, retrospective study included 29 procedures performed on 26 patients who underwent Viabahn stent graft placement between December 2017 and November 2022. We evaluated technical and clinical success rates, periprocedural complications, and stent graft patency using contrast-enhanced computed tomography. We conducted univariate analysis to examine the risk factors associated with Viabahn stent graft occlusion.

Result: The technical success rate was 96.6% (28 of 29), and the clinical success rate was 86.2% (25 of 29). The periprocedural complication rate was 17.2% (5 of 29), consisting of 4 mild adverse events and 1 patient death. The stent graft patency rates at 1, 3, 6, 12, and 24 months were 85%, 84.2%, 77.8%, 66.7%, and 50%, respectively. Univariate analysis indicated significant correlations between the lack of antiplatelet medication (P = .00074) and SG oversize ≥ 20% (P = .047).

Conclusions: This trial demonstrated the safety and effectiveness of Viabahn stent graft placement for visceral arterial injuries with high patency rates. Additionally, this study identified the lack of antiplatelet treatment and Viabahn oversize ≥ 20% as significant risk factors for Viabahn stent graft blockage in visceral arterial injuries.

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