通过新一代测序鉴定一名中国人的新型 HLA-DQA1*05:01:16 等位基因

IF 5.9 4区医学 Q2 CELL BIOLOGY HLA Pub Date : 2024-11-20 DOI:10.1111/tan.15772

Jie Liu, Zhan-Rou Quan, Bing-Na Yang, Jia-Min Song, Hong-Yan Zou

{"title":"通过新一代测序鉴定一名中国人的新型 HLA-DQA1*05:01:16 等位基因","authors":"Jie Liu, Zhan-Rou Quan, Bing-Na Yang, Jia-Min Song, Hong-Yan Zou","doi":"10.1111/tan.15772","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p><i>HLA-DQA1*05:01:16</i> differs from <i>DQA1*05:01:01:01</i> by two nucleotide substitutions, one in exon 4 and one in intron 1.</p>\n </div>","PeriodicalId":13172,"journal":{"name":"HLA","volume":"104 5","pages":""},"PeriodicalIF":5.9000,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Identification of the Novel HLA-DQA1*05:01:16 Allele by Next Generation Sequencing in a Chinese Individual\",\"authors\":\"Jie Liu, Zhan-Rou Quan, Bing-Na Yang, Jia-Min Song, Hong-Yan Zou\",\"doi\":\"10.1111/tan.15772\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p><i>HLA-DQA1*05:01:16</i> differs from <i>DQA1*05:01:01:01</i> by two nucleotide substitutions, one in exon 4 and one in intron 1.</p>\\n </div>\",\"PeriodicalId\":13172,\"journal\":{\"name\":\"HLA\",\"volume\":\"104 5\",\"pages\":\"\"},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2024-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HLA\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/tan.15772\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HLA","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/tan.15772","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CELL BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

HLA-DQA1*05:01:16与DQA1*05:01:01:01的区别在于两个核苷酸的置换，一个位于外显子4，一个位于内含子1。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Identification of the Novel HLA-DQA1*05:01:16 Allele by Next Generation Sequencing in a Chinese Individual

HLA-DQA1*05:01:16 differs from DQA1*05:01:01:01 by two nucleotide substitutions, one in exon 4 and one in intron 1.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.