用于 BNCT 光束输出程序质量保证的丙烯酸模型的特性。

IF 1.9 4区 医学 Q2 BIOLOGY Journal of Radiation Research Pub Date : 2024-11-19 DOI:10.1093/jrr/rrae089
Nishiki Matsubayashi, Naonori Hu, Takushi Takata, Akinori Sasaki, Hiroaki Kumada, Satoshi Nakamura, Akihiko Masuda, Hiroki Tanaka
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引用次数: 0

摘要

基于加速器的硼中子俘获疗法(BNCT)系统已被批准用于医保范围内的特定病例,目前日本正在对其他系统进行新病例的临床试验。由于基于加速器的硼中子俘获疗法的发展,医学物理学的操作必须更加高效。水模型用于 BNCT 光束输出程序的质量保证(QA);然而,由于固体模型易于使用,常规质量保证首选固体模型。此外,由于某些设施的结构问题,水模型无法使用,因此固体模型更适合在不同设施进行统一测量,以比较光束输出。在本研究中,我们使用丙烯酸模型进行了辐照测试,并验证了丙烯酸模型可用于质量保证。我们通过实验和模拟评估了丙烯酸模型内部热中子通量和伽马射线剂量率的分布情况。结果表明,丙烯酸模型适用于常规质量保证和比较不同系统的射束输出。今后,还将在其他设施进行同样的辐照试验。
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Characterization of acrylic phantom for use in quality assurance of BNCT beam output procedure.

The accelerator-based boron neutron capture therapy (BNCT) system has been approved for specific cases covered by health insurance, and clinical trials for new cases in Japan are currently being conducted on other systems. Owing to the progress of accelerator-based BNCT, the operation of medical physics must be rendered more efficient. A water phantom is used for the quality assurance (QA) of the BNCT beam output procedure; however, a solid phantom is preferred for routine QA because of its ease of use. Additionally, because water phantoms cannot be readily used in some facilities owing to structural problems, solid phantoms are preferred for unified measurements at different facilities to compare beam outputs. In this study, we perform irradiation tests using an acrylic phantom and verify that an acrylic phantom can be used for QA. The distribution of thermal neutron flux and gamma-ray dose rate inside the acrylic phantom are evaluated through experiments and simulations. The results indicate that the acrylic phantom is suitable for routine QA and for comparing beam outputs among different systems. In the future, the same irradiation tests will be conducted at other facilities.

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来源期刊
CiteScore
3.60
自引率
5.00%
发文量
86
审稿时长
4-8 weeks
期刊介绍: The Journal of Radiation Research (JRR) is an official journal of The Japanese Radiation Research Society (JRRS), and the Japanese Society for Radiation Oncology (JASTRO). Since its launch in 1960 as the official journal of the JRRS, the journal has published scientific articles in radiation science in biology, chemistry, physics, epidemiology, and environmental sciences. JRR broadened its scope to include oncology in 2009, when JASTRO partnered with the JRRS to publish the journal. Articles considered fall into two broad categories: Oncology & Medicine - including all aspects of research with patients that impacts on the treatment of cancer using radiation. Papers which cover related radiation therapies, radiation dosimetry, and those describing the basis for treatment methods including techniques, are also welcomed. Clinical case reports are not acceptable. Radiation Research - basic science studies of radiation effects on livings in the area of physics, chemistry, biology, epidemiology and environmental sciences. Please be advised that JRR does not accept any papers of pure physics or chemistry. The journal is bimonthly, and is edited and published by the JRR Editorial Committee.
期刊最新文献
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