Quang Khai Dao, Thuy Quynh Mai, Thanh Van Pham, An Bang Ngac, Chi Hieu Hoang, Ewald Janssens, Hanh Hong Mai
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引用次数: 0
摘要
本文介绍了一种高灵敏度的非酶吸收型葡萄糖传感器，它将氧化锌纳米棒与亚铁氧化-二甲酚橙（FOX）测定法结合在一起。氧化锌纳米棒是在铜丝网表面成功合成的，具有结晶度高、纯度高和比表面积大的特点。该葡萄糖传感器在宽线性检测范围（0 - 6 mM）内显示出 0.394 mM-1 的高灵敏度和 0.25 mM 的低检测限。与蔗糖、麦芽糖和果糖等其他糖类相比，拟议的检测方法对葡萄糖具有极佳的选择性。通过测量人体血清中的葡萄糖浓度，证明了非酶吸光度传感器在糖尿病监测中的潜在用途，并获得了与临床分析一致的数值。
ZnO nanorods grown on Cu wire mesh provide a high sensitivity non-enzymatic absorbance glucose sensor
A highly sensitive non-enzymatic absorption-based glucose sensor is introduced that combines ZnO nanorods with the ferrous oxidation-xylenol orange (FOX) assay. ZnO nanorods were successfully synthesized on the surface of a copper wire mesh, exhibiting high crystallinity, purity, and a large surface area. The glucose sensor displays a high sensitivity of 0.394 mM−1 in a wide linear detection range (0 − 6 mM), along with a low limit of detection of 0.25 mM. The proposed assay has an excellent selectivity towards glucose compared with other sugars such as sucrose, maltose, and fructose. The potential use of the non-enzymatic absorbance sensor for diabetes monitoring is demonstrated by measuring the glucose concentration in human blood serum, obtaining values that are consistent with clinical analysis.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
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