Best evidence topic report: can intradermal sterile water injections provide effective pain relief in patients with renal colic?

A short systematic review was undertaken to assess whether intradermal sterile water injections (ISWI) provide effective pain relief in adult patients presenting to the Emergency Department (ED) with renal colic. MEDLINE, Embase, Cochrane and Google Scholar databases were searched, identifying seven relevant studies. Study information, patient characteristics, key results and methodological weaknesses were tabulated. Our results indicate that ISWI provides rapid and effective pain relief within the first 15-30 min, comparable to non-steroidal anti-inflammatory drugs, with fewer adverse effects. The short follow-up periods, exclusion of more comorbid patients and variability in study design limit the generalisability of the findings. Further research is needed to establish the long-term effectiveness of ISWI in the management of renal colic in the ED.