Elizabeth S Duan, Olivia Kosterlitz, Benjamin Kerr
{"title":"变化的媒介:流动遗传因子之间的伙伴关系促进了细菌的快速适应。","authors":"Elizabeth S Duan, Olivia Kosterlitz, Benjamin Kerr","doi":"10.1016/j.tim.2024.10.010","DOIUrl":null,"url":null,"abstract":"<p><p>While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating genes. A recent paper by Sastre-Domínguez et al. describes a novel synergistic effect of mobile elements in clinically relevant bacteria, whereby conjugative plasmids that carry transposable elements can be agents of rapid adaptive change through an elevation in transposition-mediated mutation rate.</p>","PeriodicalId":23275,"journal":{"name":"Trends in Microbiology","volume":" ","pages":""},"PeriodicalIF":14.0000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation.\",\"authors\":\"Elizabeth S Duan, Olivia Kosterlitz, Benjamin Kerr\",\"doi\":\"10.1016/j.tim.2024.10.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating genes. A recent paper by Sastre-Domínguez et al. describes a novel synergistic effect of mobile elements in clinically relevant bacteria, whereby conjugative plasmids that carry transposable elements can be agents of rapid adaptive change through an elevation in transposition-mediated mutation rate.</p>\",\"PeriodicalId\":23275,\"journal\":{\"name\":\"Trends in Microbiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":14.0000,\"publicationDate\":\"2024-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Microbiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1016/j.tim.2024.10.010\",\"RegionNum\":1,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.tim.2024.10.010","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation.
While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating genes. A recent paper by Sastre-Domínguez et al. describes a novel synergistic effect of mobile elements in clinically relevant bacteria, whereby conjugative plasmids that carry transposable elements can be agents of rapid adaptive change through an elevation in transposition-mediated mutation rate.
期刊介绍:
Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.