CATG:基于共线性的基因组组装校正软件。

IF 2.1 3区 生物学 Q3 GENETICS & HEREDITY G3: Genes|Genomes|Genetics Pub Date : 2024-11-22 DOI:10.1093/g3journal/jkae277
Shengcheng Zhang, Hejun Du, Xingtan Zhang, Binzhong Wang
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引用次数: 0

摘要

基因组组装错误会对下游分析产生深远影响。基于共线性的组装校正工具(CATG)旨在利用组装基因组与参考基因组之间的共线性信息纠正这些错误。CATG 提供了一个用户友好界面,用于可视化和手动纠正装配错误。它支持插入、删除、反转以及等位基因和染色体交换等各种操作。每次修改后,软件都会自动重新聚类、重新标记和重新绘制装配图,确保用户可以轻松跟踪变化。CATG 是一款功能强大的工具,可有效纠正多倍体基因组中的大规模组装错误,具有先进的共线性检测功能。
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CATG: Software for Collinearity-Based Genome Assembly Correction.

Genome assembly errors can have a profound effect on downstream analyses. Collinearity-based Assembly Correction Tool (CATG) is designed to rectify these errors by leveraging collinearity information between the assembled genome and a reference genome. CATG provides a user-friendly interface for visualizing and manually correcting assembly errors. It supports various operations such as insertion, deletion, inversion, and swapping of contigs and chromosomes. The software automatically re-clusters, re-labels, and re-draws the assembly after each modification, ensuring that users can easily track changes. CATG is a robust tool designed to efficiently correct large-scale assembly errors in polyploid genomes, featuring advanced collinearity detection capabilities.

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来源期刊
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics GENETICS & HEREDITY-
CiteScore
5.10
自引率
3.80%
发文量
305
审稿时长
3-8 weeks
期刊介绍: G3: Genes, Genomes, Genetics provides a forum for the publication of high‐quality foundational research, particularly research that generates useful genetic and genomic information such as genome maps, single gene studies, genome‐wide association and QTL studies, as well as genome reports, mutant screens, and advances in methods and technology. The Editorial Board of G3 believes that rapid dissemination of these data is the necessary foundation for analysis that leads to mechanistic insights. G3, published by the Genetics Society of America, meets the critical and growing need of the genetics community for rapid review and publication of important results in all areas of genetics. G3 offers the opportunity to publish the puzzling finding or to present unpublished results that may not have been submitted for review and publication due to a perceived lack of a potential high-impact finding. G3 has earned the DOAJ Seal, which is a mark of certification for open access journals, awarded by DOAJ to journals that achieve a high level of openness, adhere to Best Practice and high publishing standards.
期刊最新文献
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