用于术中电子放疗的 PVA/MWCNT-OH 纳米复合材料剂量学特性探讨

IF 1.6 3区物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Radiation Measurements Pub Date : 2024-11-18 DOI:10.1016/j.radmeas.2024.107345

Shahryar Malekie , Seyed Rashid Hosseini Aghdam , Seyed Mahmoud Reza Aghamiri , Armin Mosayebi , Suffian Mohamad Tajudin

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引用次数: 0

摘要

本研究调查了用于术中电子放射治疗（IOeRT）的聚乙烯醇/多壁碳纳米管羟基（PVA/MWCNT-OH）复合材料的剂量特性。使用 0.02 wt% MWCNT-OH 纳米复合材料制作了剂量计，其厚度为 2 毫米，直径为 2 厘米。辐照期间记录的电荷作为该实时剂量计的响应。对 8 MeV IOeRT 的剂量测定类型测试标准进行了评估，包括响应线性、剂量率、偏置极性、可重复性、磁场大小以及对电子能量的依赖性等方面。为了评估能量依赖性，利用 LIAC 专用 IOeRT 设备在不同能量（包括 6、8、10 和 12 MeV）下对剂量计的响应进行了测量。结果表明，在吸收剂量高达 17 Gy 时，剂量计的响应呈线性相关。此外，各种类型测试评估表明，除了能量依赖性需要应用适当的校正因子外，剂量计符合 IEC 60731 标准。

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Exploration of dosimetry characteristics of PVA/MWCNT-OH nanocomposite for intraoperative electron radiotherapy

This study investigates the dosimetric properties of a Polyvinyl Alcohol/Multi-Walled Carbon Nanotube Hydroxyl (PVA/MWCNT-OH) composite intended for intraoperative electron radiotherapy (IOeRT). A dosimeter was fabricated using a 0.02 wt% MWCNT-OH nanocomposite, featuring a thickness of 2 mm and a diameter of 2 cm. The electric charge recorded during irradiation served as the response for this real-time dosimeter. The dosimetry type-testing criteria for IOeRT at 8 MeV were evaluated, encompassing aspects such as linearity of response, dose rate, bias polarity, repeatability, field size, and dependency on electron energy. To assess energy dependency, the dosimeter's response was measured at various energies including 6, 8, 10, and 12 MeV utilizing a LIAC dedicated IOeRT machine. The results indicated a linear correlation in the dosimeter's response across absorbed doses up to 17 Gy. Furthermore, the various type-testing evaluations demonstrated compliance with IEC 60731 standard, with the exception of energy dependency, which necessitates the application of a suitable correction factor.

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来源期刊

Radiation Measurements 工程技术-核科学技术

CiteScore

4.10

自引率

20.00%

发文量

116

审稿时长

48 days

期刊介绍： The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.