Ming-Jen Cheng , Jih-Jung Chen , Hsia-Wei Liu , Ming-Der Wu , Yu-Hui Wei , Guey-Yuh Liou , Min Tseng
{"title":"从毛霉 18F0056 培养基中提取天然产物并评估其抗真菌特性","authors":"Ming-Jen Cheng , Jih-Jung Chen , Hsia-Wei Liu , Ming-Der Wu , Yu-Hui Wei , Guey-Yuh Liou , Min Tseng","doi":"10.1016/j.phytol.2024.10.009","DOIUrl":null,"url":null,"abstract":"<div><div>Two previously undescribed chromone derivatives, <strong>1</strong> and <strong>2</strong>, were isolated from the EtOAc-soluble fraction of the culture broth of <em>Trichoderma</em> sp. 18F0056. Their structures were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that both constituents possessed weak antifungal activity against <em>Fusarium</em> sp. LC8, <em>Neopestalotiopsis</em> sp. BCRC 35002, and <em>Colletotrichum gloeosporioides</em> BCRC 35178. In the past, chromone derivatives were rarely found from the genus <em>Trichoderma</em>. This time, the research on the products of this new species of <em>Trichoderma</em> is of significant significance. <em>Trichoderma</em> natural products deserve further evaluation as anti-fungal agents for biocontrol.</div></div>","PeriodicalId":20408,"journal":{"name":"Phytochemistry Letters","volume":"65 ","pages":"Pages 44-47"},"PeriodicalIF":1.3000,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extraction and assessment of antifungal properties of natural products from the culture medium of Trichoderma sp. 18F0056\",\"authors\":\"Ming-Jen Cheng , Jih-Jung Chen , Hsia-Wei Liu , Ming-Der Wu , Yu-Hui Wei , Guey-Yuh Liou , Min Tseng\",\"doi\":\"10.1016/j.phytol.2024.10.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Two previously undescribed chromone derivatives, <strong>1</strong> and <strong>2</strong>, were isolated from the EtOAc-soluble fraction of the culture broth of <em>Trichoderma</em> sp. 18F0056. Their structures were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that both constituents possessed weak antifungal activity against <em>Fusarium</em> sp. LC8, <em>Neopestalotiopsis</em> sp. BCRC 35002, and <em>Colletotrichum gloeosporioides</em> BCRC 35178. In the past, chromone derivatives were rarely found from the genus <em>Trichoderma</em>. This time, the research on the products of this new species of <em>Trichoderma</em> is of significant significance. <em>Trichoderma</em> natural products deserve further evaluation as anti-fungal agents for biocontrol.</div></div>\",\"PeriodicalId\":20408,\"journal\":{\"name\":\"Phytochemistry Letters\",\"volume\":\"65 \",\"pages\":\"Pages 44-47\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-11-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phytochemistry Letters\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1874390024001460\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phytochemistry Letters","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1874390024001460","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Extraction and assessment of antifungal properties of natural products from the culture medium of Trichoderma sp. 18F0056
Two previously undescribed chromone derivatives, 1 and 2, were isolated from the EtOAc-soluble fraction of the culture broth of Trichoderma sp. 18F0056. Their structures were elucidated on the basis of extensive analyses of spectroscopic data and comparison with literature data. Their antifungal activity was also evaluated. Our results showed that both constituents possessed weak antifungal activity against Fusarium sp. LC8, Neopestalotiopsis sp. BCRC 35002, and Colletotrichum gloeosporioides BCRC 35178. In the past, chromone derivatives were rarely found from the genus Trichoderma. This time, the research on the products of this new species of Trichoderma is of significant significance. Trichoderma natural products deserve further evaluation as anti-fungal agents for biocontrol.
期刊介绍：
Phytochemistry Letters invites rapid communications on all aspects of natural product research including:
• Structural elucidation of natural products
• Analytical evaluation of herbal medicines
• Clinical efficacy, safety and pharmacovigilance of herbal medicines
• Natural product biosynthesis
• Natural product synthesis and chemical modification
• Natural product metabolism
• Chemical ecology
• Biotechnology
• Bioassay-guided isolation
• Pharmacognosy
• Pharmacology of natural products
• Metabolomics
• Ethnobotany and traditional usage
• Genetics of natural products
Manuscripts that detail the isolation of just one new compound are not substantial enough to be sent out of review and are out of scope. Furthermore, where pharmacology has been performed on one new compound to increase the amount of novel data, the pharmacology must be substantial and/or related to the medicinal use of the producing organism.
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