用于治疗细菌感染伤口的抗菌水凝胶

Wenhan Li , Quanchi Chen , Yanyu Ma , Haiwen Su , Haoyu Ren , Huan Wang
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引用次数: 0

摘要

细菌感染伤口是巨大的临床障碍,给患者和社会造成了巨大负担。近年来,许多生物材料被设计用于治疗细菌感染伤口。在各种生物材料中,抗菌水凝胶是最值得推荐的一类,因为它既能负载抗菌药物,又能覆盖伤口,同时还能保持湿润的环境。在这篇综述中,我们将介绍用于细菌感染伤口治疗的抗菌水凝胶的研究进展。我们首先总结了细菌感染伤口的病理生理学,展示了其临床表现,并提供了临床治疗项目。随后,我们介绍了抗菌水凝胶的不同形态。然后,重点介绍了抗菌水凝胶的各种实际应用和治疗效果。最后,总结了抗菌水凝胶在细菌感染伤口愈合方面的最新问题和前景。希望这篇综述能对细菌感染伤口治疗及相关生物医学领域的发展有所启发。
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Antibacterial hydrogels for bacteria-infected wound treatment
Bacteria-infected wounds are enormous clinical obstacles and cause huge burdens to patients and society. Recently, many biomaterials are designed to treat bacterial infected wounds. Among various biomaterials, antibacterial hydrogels are one of the most recommended groups due to their ability to load antibacterial drugs and cover wounds while maintaining a moist environment. In this review, we present the progress in antibacterial hydrogels for bacteria-infected wound treatment. We first summarize the pathophysiology of bacteria-infected wounds, which demonstrates the clinical manifestations and offers clinical therapy projects. Afterwards, we describe the different morphologies of antibacterial hydrogels. Then, we focus on the various practical applications and therapeutic effects of antibacterial hydrogels. At last, the recent problems and outlook of antibacterial hydrogels for bacteria-infected wound healing are summarized. We hope this review can inspire the development of bacteria-infected wound treatment and the related biomedical fields.
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