肌肉疏松症的发病率及其对多发性创伤结果的影响。

Q4 Medicine Georgian medical news Pub Date : 2024-09-01
H Asim, A Sain, N Manzoor, M Nausherwan, M Malik, F Hussain, M Bilal, H Khan, A Varasteh, A Jindal, M Sohail, N Khayyat, K Wattage, M Halasa, J Chia, J Wilson
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引用次数: 0

摘要

背景:肌少症对人口数量有负面影响。然而,人们对多发性创伤患者肌肉疏松症的发病率知之甚少。目的:这项试点研究的目标包括确定老年多发性创伤患者肌肉质量低的患病率,并研究并发症、肌肉质量低、死亡和炎症反应之间的联系:所有在2017年至2021年期间在一级创伤中心就诊的多发性创伤患者均被纳入创伤区域透视登记数据。对受试者的腹部可用性和身高进行计算机断层扫描(CT)筛查,以确定骨骼质量指数(SMI),用于计算肌肉疏松症。此外,还对临床结果因素进行了评估。如果通过单变量分析发现与不良结果相关的参数,则进行多变量回归分析:总体而言,33.5%的人口患有肌肉疏松症,但在年龄较大的群体(60-79 岁)中,其患病率明显更高,80 岁以上人群的患病率高达 82%。ISS(受伤严重程度评分)的 p=0.026,年龄的 p=0.026:总之,我们发现多发性创伤患者的肌肉疏松症发病率很高,且随着年龄的增长而增加。此外,我们还发现肌肉疏松症是 30 天死亡的预测因素,这突出了在 CT 扫描中发现低肌肉质量的临床重要性。
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THE PREVALENCE OF SARCOPENIA AND ITS EFFECTS ON OUTCOMES IN POLYTRAUMA.

Background: Sarcopenia has a negative impact on the number of populations. The frequency of sarcopenia in polytrauma patients, however, is little understood. Knowing how many people face a bad outcome will raise awareness and help stop additional muscle mass loss.

Aim: This pilot study's objectives included determining prevalence of the low mass of muscle in the aged patients of poly-trauma and examining the links between complications, low muscle mass, death, and the inflammatory response.

Method: All polytrauma patients who were seen between 2017 and 2021 at the level-I trauma centre were included in the data from the regional perspective registry of trauma. The computed tomography (CT) of the abdomen's availability and the height in the subjects was screened to determine the skeletal mass index (SMI), which is utilised to calculate the sarcopenia. Additionally, factors of clinical outcome were evaluated. A multivariate regression analysis was conducted if parameters related to a poor result were found through a univariate analysis.

Results: Sarcopenia was prevalent in 33.5 percent of the population overall, but in older age groups (60-79 years), it was significantly more prevalent, reaching to 82 percent in the individuals over the 80 years old. The ISS (Injury severity score) where the p=0.026, age where the p<0.0001, the CCI (Charlson comorbidity index) where the p=0.001, injury severity score, and the 30-day or the in-hospital mortality were all associated with sarcopenia. The Injury Severity Score (ISS) is a medical scoring system to assess trauma severity based on the extent of injuries in various body regions. Sarcopenia was discovered to be a predictor of the 30-day mortality by log rank analysis (p=0.032).

Conclusion: In conclusion, we found that polytrauma patients had a significant prevalence of sarcopenia, which increased with age. Additionally, sarcopenia was found to be the predictor of the 30-day death, highlighting clinical importance of finding the low muscle mass on the CT-scan, which was already regularly performed on the majority of patients of trauma.

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来源期刊
Georgian medical news
Georgian medical news Medicine-Medicine (all)
CiteScore
0.60
自引率
0.00%
发文量
207
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