中国急性A型主动脉夹层患者再次入住ICU的预测模型:一项回顾性研究。

IF 3.3 3区 医学 Q2 MEDICAL INFORMATICS BMC Medical Informatics and Decision Making Pub Date : 2024-11-26 DOI:10.1186/s12911-024-02770-2
Hong Ni, Yanchun Peng, Qiong Pan, Zhuling Gao, Sailan Li, Liangwan Chen, Yanjuan Lin
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引用次数: 0

摘要

背景:重症监护室(ICU)再入院仍然是一个严峻的挑战,会导致更高的死亡率和更大的经济负担。本研究旨在为急性 A 型主动脉夹层(ATAAD)患者建立一个基于提名图的预测模型:2014年5月至2021年10月期间,共回顾性登记了846名ATAAD患者。采用逻辑回归确定独立风险因素。预测模型采用 Hosmer-Lemeshow (H-L) 检验、校准曲线和接收者工作特征曲线下面积 (AUC) 进行评估。决策曲线分析(DCA)用于评估临床实用性:结果:57 名(6.7%)ATAAD 患者从重症监护室出院后再次入住重症监护室。年龄≥65岁、体重指数(BMI)≥28 kg/m2、气管切开术、持续肾脏替代治疗(CRRT)和最初入住ICU的时间是ICU再入院的预测因素。AUC为0.837(95%CI:0.789-0.884),模型与数据拟合良好(H-L检验,P = 0.519)。DCA也显示出良好的临床实用性:该预测模型有助于临床医生评估重症监护室再入院风险,并有助于早期识别高风险的 ATAAD 患者。
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Prediction model of ICU readmission in Chinese patients with acute type A aortic dissection: a retrospective study.

Background: Readmission to the intensive care unit (ICU) remains a severe challenge, leading to higher rates of death and a greater financial burden. This study aimed to develop a nomogram-based prediction model for individuals with acute type A aortic dissection (ATAAD).

Methods: A total of 846 ATAAD patients were retrospectively enrolled between May 2014 and October 2021. Logistic regression was employed to identify the independent risk factors. The prediction model was evaluated using the Hosmer-Lemeshow (H-L) test, the calibration curve, and the area under the receiver operating characteristic curve (AUC). Decision curve analysis (DCA) was used to assess the clinical utility.

Results: 57 (6.7%) ATAAD patients were readmitted to ICU following their release from the ICU. ICU readmission was predicted with age ≥ 65 years old, body mass index (BMI) ≥ 28 kg/m2, tracheotomy, continuous renal replacement therapy (CRRT), and the length of initial ICU stay were predictors of ICU readmission. The AUC was 0.837 (95%CI: 0.789-0.884) and the model fit the data well (H-L test, P = 0.519). DCA also demonstrated good clinical practicability.

Conclusions: This prediction model may be helpful for clinicians to assess the risk of ICU readmission, and facilitate the early identification of ATAAD patients at high risk.

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来源期刊
CiteScore
7.20
自引率
5.70%
发文量
297
审稿时长
1 months
期刊介绍: BMC Medical Informatics and Decision Making is an open access journal publishing original peer-reviewed research articles in relation to the design, development, implementation, use, and evaluation of health information technologies and decision-making for human health.
期刊最新文献
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