{"title":"腹泻和肺炎是氯氮平治疗带来的最大负担","authors":"","doi":"10.1002/pu.31253","DOIUrl":null,"url":null,"abstract":"<p>An analysis of longitudinal data with up to 25 years of follow-up has identified five disease categories for which clozapine use was associated with higher risk of adverse drug events. The Finnish study found higher-than-expected prevalence of ileus and pneumonia in patients receiving clozapine, with both illnesses associated with greater mortality.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 1","pages":"4-5"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ileus, pneumonia among most burdensome effects of clozapine treatment\",\"authors\":\"\",\"doi\":\"10.1002/pu.31253\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>An analysis of longitudinal data with up to 25 years of follow-up has identified five disease categories for which clozapine use was associated with higher risk of adverse drug events. The Finnish study found higher-than-expected prevalence of ileus and pneumonia in patients receiving clozapine, with both illnesses associated with greater mortality.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"36 1\",\"pages\":\"4-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31253\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31253","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ileus, pneumonia among most burdensome effects of clozapine treatment
An analysis of longitudinal data with up to 25 years of follow-up has identified five disease categories for which clozapine use was associated with higher risk of adverse drug events. The Finnish study found higher-than-expected prevalence of ileus and pneumonia in patients receiving clozapine, with both illnesses associated with greater mortality.
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