狮子(Panthera leo)弥漫性虹膜黑色素瘤导致继发性青光眼1例报告。

IF 1.7 4区 农林科学 Q2 VETERINARY SCIENCES Veterinary ophthalmology Pub Date : 2024-12-01 DOI:10.1111/vop.13307
Jade Caproni Correa, Matheus Vilardo Lóes Moreira, Manoel Lucas Javorouski, Juliana Werner, Gillian Shaw, Barbara Schreider, Ricardo Guilherme D'Otaviano de Castro Vilani, Fabiano Montiani-Ferreira
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引用次数: 0

摘要

摘要目的:描述一只12岁雄性非洲狮(Panthera leo)的病例,其表现为眼部分泌物、角膜水肿和右眼大眼肿大。手术过程:眼部超声检查显示眼内肿块累及虹膜和睫状体。行去核术。结果:随后的组织病理学分析显示多形性色素肿瘤细胞群浸润、扩张和消除虹膜和睫状体,并占据睫状体间隙。组织病理学和免疫组织化学特征符合弥漫性虹膜黑色素瘤(DIM)。结论:DIM是家猫最常见的原发性眼内肿瘤,但在大型猫科动物中很少报道。大面积地区的预后尚不清楚,需要确定更多病例并仔细监测受影响的个体。
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Diffuse iris melanoma leading to secondary glaucoma in a lion (Panthera leo)-A case report.

Objective: To describe the case of a 12-year-old male African lion (Panthera leo) presented with ocular discharge, corneal edema, and buphthalmos of the right eye.

Procedures: Ocular ultrasonography showed an intraocular mass involving the iris and ciliary body. Enucleation was performed.

Results: Subsequent histopathological analysis revealed a pleomorphic pigmented neoplastic cell population infiltrating, expanding and effacing the iris and ciliary body and occupying the ciliary cleft. The histopathological and immunohistochemical features were consistent with a diffuse iris melanoma (DIM).

Conclusion: DIM is the most common primary intraocular neoplasm of domestic cats, but rarely reported in large felids. The prognosis in large felids is unknown and warrants identifying additional cases and careful monitoring of affected individuals.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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