Jade Caproni Correa, Matheus Vilardo Lóes Moreira, Manoel Lucas Javorouski, Juliana Werner, Gillian Shaw, Barbara Schreider, Ricardo Guilherme D'Otaviano de Castro Vilani, Fabiano Montiani-Ferreira
{"title":"狮子(Panthera leo)弥漫性虹膜黑色素瘤导致继发性青光眼1例报告。","authors":"Jade Caproni Correa, Matheus Vilardo Lóes Moreira, Manoel Lucas Javorouski, Juliana Werner, Gillian Shaw, Barbara Schreider, Ricardo Guilherme D'Otaviano de Castro Vilani, Fabiano Montiani-Ferreira","doi":"10.1111/vop.13307","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To describe the case of a 12-year-old male African lion (Panthera leo) presented with ocular discharge, corneal edema, and buphthalmos of the right eye.</p><p><strong>Procedures: </strong>Ocular ultrasonography showed an intraocular mass involving the iris and ciliary body. Enucleation was performed.</p><p><strong>Results: </strong>Subsequent histopathological analysis revealed a pleomorphic pigmented neoplastic cell population infiltrating, expanding and effacing the iris and ciliary body and occupying the ciliary cleft. The histopathological and immunohistochemical features were consistent with a diffuse iris melanoma (DIM).</p><p><strong>Conclusion: </strong>DIM is the most common primary intraocular neoplasm of domestic cats, but rarely reported in large felids. The prognosis in large felids is unknown and warrants identifying additional cases and careful monitoring of affected individuals.</p>","PeriodicalId":23836,"journal":{"name":"Veterinary ophthalmology","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diffuse iris melanoma leading to secondary glaucoma in a lion (Panthera leo)-A case report.\",\"authors\":\"Jade Caproni Correa, Matheus Vilardo Lóes Moreira, Manoel Lucas Javorouski, Juliana Werner, Gillian Shaw, Barbara Schreider, Ricardo Guilherme D'Otaviano de Castro Vilani, Fabiano Montiani-Ferreira\",\"doi\":\"10.1111/vop.13307\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To describe the case of a 12-year-old male African lion (Panthera leo) presented with ocular discharge, corneal edema, and buphthalmos of the right eye.</p><p><strong>Procedures: </strong>Ocular ultrasonography showed an intraocular mass involving the iris and ciliary body. Enucleation was performed.</p><p><strong>Results: </strong>Subsequent histopathological analysis revealed a pleomorphic pigmented neoplastic cell population infiltrating, expanding and effacing the iris and ciliary body and occupying the ciliary cleft. The histopathological and immunohistochemical features were consistent with a diffuse iris melanoma (DIM).</p><p><strong>Conclusion: </strong>DIM is the most common primary intraocular neoplasm of domestic cats, but rarely reported in large felids. The prognosis in large felids is unknown and warrants identifying additional cases and careful monitoring of affected individuals.</p>\",\"PeriodicalId\":23836,\"journal\":{\"name\":\"Veterinary ophthalmology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary ophthalmology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1111/vop.13307\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary ophthalmology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/vop.13307","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Diffuse iris melanoma leading to secondary glaucoma in a lion (Panthera leo)-A case report.
Objective: To describe the case of a 12-year-old male African lion (Panthera leo) presented with ocular discharge, corneal edema, and buphthalmos of the right eye.
Procedures: Ocular ultrasonography showed an intraocular mass involving the iris and ciliary body. Enucleation was performed.
Results: Subsequent histopathological analysis revealed a pleomorphic pigmented neoplastic cell population infiltrating, expanding and effacing the iris and ciliary body and occupying the ciliary cleft. The histopathological and immunohistochemical features were consistent with a diffuse iris melanoma (DIM).
Conclusion: DIM is the most common primary intraocular neoplasm of domestic cats, but rarely reported in large felids. The prognosis in large felids is unknown and warrants identifying additional cases and careful monitoring of affected individuals.
期刊介绍:
Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of:
Clinical and investigational veterinary and comparative ophthalmology;
Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species;
Experimental models of both animal and human ocular disease in veterinary species;
Anatomic studies of the animal eye;
Physiological studies of the animal eye;
Pharmacological studies of the animal eye.