机器人挽救性根治性子宫切除术治疗局部复发宫颈癌:与开放手术在单外科系列中的比较。

IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY Journal of Obstetrics and Gynaecology Research Pub Date : 2024-12-04 DOI:10.1111/jog.16142
Seiji Mabuchi, Michihide Maeda, Mina Sakata, Shinya Matsuzaki, Yuri Matsumoto, Shoji Kamiura, Tadashi Kimura
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引用次数: 0

摘要

目的:比较局部复发宫颈癌患者接受机器人辅助补救性根治性子宫切除术(RH)和接受常规开放式补救性子宫切除术(RH)的手术和肿瘤预后。方法:这项回顾性比较观察性研究利用了连续的局部复发宫颈癌患者的数据,这些患者是在明确的放射治疗后发生的。这些患者要么接受机器人辅助RH(机器人组),要么接受传统的开放式RH(开放组)。比较两组患者的临床病理特征、手术结果和肿瘤结果。结果:机器人组手术时间稍长;然而,这种差异在统计学上并不显著。机器人组的估计失血量显著降低(中位数;0 mL[机器人组]vs. 700 mL[开放组]:p结论:机器人辅助的补救性RH在局部复发宫颈癌妇女中的围手术期和肿瘤预后与开放手术相当。尽管我们的研究结果表明,机器人辅助的方法与开放的方法一样好,甚至更好,但需要进一步的研究来建立一个更有力的结论。
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Robotic salvage radical hysterectomy for locally recurrent cervical cancer: A comparison with open surgery in a single-surgeon series

Aim

To compare the surgical and oncologic outcomes between patients with locally recurrent cervical cancer undergoing robotic-assisted salvage radical hysterectomy (RH) and those undergoing conventional open salvage RH, performed by a single surgeon.

Methods

This retrospective comparative observational study utilized data obtained from consecutive patients with locally recurrent cervical cancer, developed after definitive radiotherapy. These patients either underwent robot-assisted RH (robotic group) or conventional open RH (open group). Clinicopathological characteristics, surgical outcomes, and oncological outcomes were compared between the two groups.

Results

The operative time was slightly longer in the robotic group; however, this difference was not statistically significant. Estimated blood loss was significantly lower in the robotic group (median; 0 mL [robotic group] vs. 700 mL [open group]: p < 0.01). The incidence of intraoperative and early and late complications did not statistically differ between the two groups. The mean follow-up was 29.0 and 17.1 months in the open and robotic groups, respectively. Disease recurrence rates were similar between the two groups (40% [robotic group] vs. 44.4% [open group]). Kaplan–Meier survival analysis for progression-free survival and overall survival did not show statistically significant differences between the two groups.

Conclusion

Robot-assisted salvage RH in women with locally recurrent cervical cancer showed perioperative and oncological outcomes comparable to those of the open procedure. Although our results suggest that the robot-assisted approach is as good as or better than the open approach, further investigation is required to establish a more robust conclusion.

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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
376
审稿时长
3-6 weeks
期刊介绍: The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.
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