68Ga-FAPI PET/CT显示免疫功能低下的胰腺癌患者的热带念珠菌肝脓肿。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-12-05 DOI:10.1097/RLU.0000000000005633

Jahae Kim, Seong Eun Kim, Eunae Cho, Kang-Ho Choi

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摘要

摘要：念珠菌感染已成为肿瘤免疫功能低下患者日益关注的问题。我们在68Ga-FAPI PET/CT上报告一例免疫功能低下的胰头癌患者肝脓肿引起热带念珠菌。患者77岁，既往糖尿病未控制10年，存在中性粒细胞减少，免疫功能低下，经14个周期化疗和姑息性放疗仍进展为胰腺癌。放疗3周后，患者出现发热及CRP水平升高。68Ga-FAPI PET/CT扫描显示肝脏出现新的强烈摄取，2对血培养显示热带镰刀菌。

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Candida tropicalis Liver Abscess in an Immunocompromised Patient With Pancreatic Head Cancer on 68 Ga-FAPI PET/CT.

Abstract: Candida infections have become a growing concern to the immunocompromised patients with cancer. We report a case of liver abscess causing Candida tropicalis candidemia in an immunocompromised patient with pancreatic head cancer on 68 Ga-FAPI PET/CT. A 77-year-old man had a history of 10-year duration of uncontrolled diabetes, the presence of neutropenia, immunocompromised condition, and the progression of pancreatic cancer despite the 14 cycles of chemotherapy and palliative radiotherapy. After 3 weeks of radiotherapy, he presented with fever and elevated CRP level. 68 Ga-FAPI PET/CT scan showed new intense uptake in the liver, and 2 pairs of blood culture revealed C. tropicalis.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.