血管细胞遍布人体的血管和器官

IF 50 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nature Medicine Pub Date : 2024-12-06 DOI:10.1038/s41591-024-03410-y

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引用次数: 0

摘要

血管系统除了在氧气和营养物质运输中的作用外，在人体中还有许多不同的功能。通过整合来自人类细胞图谱的单细胞rna测序数据和正在进行的19个健康人体器官和组织的合作，我们探索了血管细胞的异质性，并强调了血管床的共同和独特的分子特征。

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Vascular cells of blood vessels and organs across the human body

The vascular system has many different functions across the human body beyond its role in oxygen and nutrient transport. We explored vascular cell heterogeneity by integrating single-cell RNA-sequencing data from the Human Cell Atlas and ongoing collaborations across 19 healthy human organs and tissues, and highlight shared and distinct molecular features of vascular beds.

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.