利用空间蛋白质组学和视觉智能革新癌症研究

IF 36.1 1区生物学 Q1 BIOCHEMICAL RESEARCH METHODS Nature Methods Pub Date : 2024-12-06 DOI:10.1038/s41592-024-02542-w

Daniela F. Quail, Logan A. Walsh

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引用次数: 0

摘要

空间蛋白质组学通过提供对肿瘤微环境景观的无与伦比的见解，改变了癌症研究。在这里，我们讨论了这些技术如何显著提高我们对细胞-细胞相互作用、组织组织和抗肿瘤免疫反应的空间协调机制的理解，并将为癌症研究的新突破铺平道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revolutionizing cancer research with spatial proteomics and visual intelligence

Spatial proteomics has transformed cancer research by providing unparalleled insights into the microenvironmental landscape of tumors. Here we discuss how these technologies have significantly advanced our understanding of cell–cell interactions, tissue organization and spatially coordinated mechanisms underlying antitumor immune responses, and will pave the way for emerging breakthroughs in cancer research.

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来源期刊

Nature Methods 生物-生化研究方法

CiteScore

58.70

自引率

1.70%

发文量

326

审稿时长

1 months

期刊介绍： Nature Methods is a monthly journal that focuses on publishing innovative methods and substantial enhancements to fundamental life sciences research techniques. Geared towards a diverse, interdisciplinary readership of researchers in academia and industry engaged in laboratory work, the journal offers new tools for research and emphasizes the immediate practical significance of the featured work. It publishes primary research papers and reviews recent technical and methodological advancements, with a particular interest in primary methods papers relevant to the biological and biomedical sciences. This includes methods rooted in chemistry with practical applications for studying biological problems.