个性化纳米医学的人工智能;从材料选择到患者结果。

Expert opinion on drug delivery Pub Date : 2025-01-01 Epub Date: 2024-12-15 DOI:10.1080/17425247.2024.2440618
Hirak Mazumdar, Kamil Reza Khondakar, Suparna Das, Animesh Halder, Ajeet Kaushik
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引用次数: 0

摘要

将人工智能(AI)应用于纳米医学,大大增加了用于定制药物的特殊工程纳米材料的生产,标志着医疗保健领域的重大进步。通过使用人工智能,研究人员可以在庞大的数据库中搜索,找到支持一系列治疗目标的纳米特性,最终生产出更安全、定制的纳米材料。人工智能分析患者数据,包括临床和遗传信息,以预测个性化护理的结果,并提出改进治疗的建议。此外,人工智能在逻辑上创造了纳米载体,提供精确和可控的药物释放模式,优化治疗优势,最大限度地减少不良副作用。尽管人工智能在纳米医学方面有很大的潜力,但仍然存在数据集成技术、道德困境、政府支持的要求等问题。人工智能工具的未来发展以及具有生物科学和纳米工程专业知识的科学家之间的多学科合作对于个性化纳米医学至关重要。总之,这些学科可以推动人工智能和精准医学的进步,为最终目标做出贡献——人工智能和纳米医学结合起来,提供真正个性化的医疗保健。这篇社论的作者鼓励在纳米医学中使用人工智能,并呼吁科学家、医生和立法者承认其改变患者护理和治疗的潜力。
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Artificial intelligence for personalized nanomedicine; from material selection to patient outcomes.

Introduction: Artificial intelligence (AI) is changing the field of nanomedicine by exploring novel nanomaterials for developing therapies of high efficacy. AI works on larger datasets, finding sought-after nano-properties for different therapeutic aims and eventually enhancing nanomaterials' safety and effectiveness. AI leverages patient clinical and genetic data to predict outcomes, guide treatments, and optimize drug dosages and forms, enhancing benefits while minimizing side effects. AI-supported nanomedicine faces challenges like data fusion, ethics, and regulation, requiring better tools and interdisciplinary collaboration. This review highlights the importance of AI regarding patient care and urges scientists, medical professionals, and regulators to adopt AI for better outcomes.

Areas covered: Personalized Nanomedicine, Material Discovery, AI-Driven Therapeutics, Data Integration, Drug Delivery, Patient Centric Care.

Expert opinion: Today, AI can improve personalized health wellness through the discovery of new types of drug nanocarriers, nanomedicine of specific properties to tackle targeted medical needs, and an increment in efficacy along with safety. Nevertheless, problems such as ethical issues, data security, or unbalanced data sets need to be addressed. Potential future developments involve using AI and quantum computing together and exploring telemedicine i.e. the Internet-of-Medical-Things (IoMT) approach can enhance the quality of patient care in a personalized manner by timely decision-making.

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