Antonio Loforte, Matteo Marro, Erika Simonato, Andrea Costamagna, Marco Ellena, Anna Chiara Trompeo, Marinella Zanierato, Luca Brazzi, Mauro Rinaldi, Massimo Boffini
{"title":"循环性死亡后控制捐献心脏异体移植物获取和灌注的外科技术。","authors":"Antonio Loforte, Matteo Marro, Erika Simonato, Andrea Costamagna, Marco Ellena, Anna Chiara Trompeo, Marinella Zanierato, Luca Brazzi, Mauro Rinaldi, Massimo Boffini","doi":"10.21037/acs-2024-dcd-26","DOIUrl":null,"url":null,"abstract":"<p><p>In the last decade, heart transplants using allografts from adult donors after circulatory death, in a controlled setting, controlled donation after circulatory death (cDCD) have been rapidly adopted and widely performed. The selection of retrieval methods has largely been determined by state or institutional guidelines concerning permissible postmortem procedures. A significant majority of cDCD heart recoveries have employed direct procurement and perfusion (DPP) followed by normothermic machine perfusion (NMP) for graft preservation. Another established method involves the thoracoabdominal normothermic regional perfusion (taNRP), which is then followed by either NMP or static cold storage. Processing, management and surgical techniques of heart allograft procurement after cDCD are herein described and discussed.</p>","PeriodicalId":8067,"journal":{"name":"Annals of cardiothoracic surgery","volume":"13 6","pages":"522-530"},"PeriodicalIF":3.3000,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618125/pdf/","citationCount":"0","resultStr":"{\"title\":\"Surgical techniques for cardiac allograft procurement and perfusion in controlled donation after circulatory death.\",\"authors\":\"Antonio Loforte, Matteo Marro, Erika Simonato, Andrea Costamagna, Marco Ellena, Anna Chiara Trompeo, Marinella Zanierato, Luca Brazzi, Mauro Rinaldi, Massimo Boffini\",\"doi\":\"10.21037/acs-2024-dcd-26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In the last decade, heart transplants using allografts from adult donors after circulatory death, in a controlled setting, controlled donation after circulatory death (cDCD) have been rapidly adopted and widely performed. The selection of retrieval methods has largely been determined by state or institutional guidelines concerning permissible postmortem procedures. A significant majority of cDCD heart recoveries have employed direct procurement and perfusion (DPP) followed by normothermic machine perfusion (NMP) for graft preservation. Another established method involves the thoracoabdominal normothermic regional perfusion (taNRP), which is then followed by either NMP or static cold storage. Processing, management and surgical techniques of heart allograft procurement after cDCD are herein described and discussed.</p>\",\"PeriodicalId\":8067,\"journal\":{\"name\":\"Annals of cardiothoracic surgery\",\"volume\":\"13 6\",\"pages\":\"522-530\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618125/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of cardiothoracic surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21037/acs-2024-dcd-26\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/11/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of cardiothoracic surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/acs-2024-dcd-26","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/26 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Surgical techniques for cardiac allograft procurement and perfusion in controlled donation after circulatory death.
In the last decade, heart transplants using allografts from adult donors after circulatory death, in a controlled setting, controlled donation after circulatory death (cDCD) have been rapidly adopted and widely performed. The selection of retrieval methods has largely been determined by state or institutional guidelines concerning permissible postmortem procedures. A significant majority of cDCD heart recoveries have employed direct procurement and perfusion (DPP) followed by normothermic machine perfusion (NMP) for graft preservation. Another established method involves the thoracoabdominal normothermic regional perfusion (taNRP), which is then followed by either NMP or static cold storage. Processing, management and surgical techniques of heart allograft procurement after cDCD are herein described and discussed.