精神病临床高危人群自杀意念和自杀未遂的发生率和临床相关性。

IF 2.1 4区 医学 Q3 PSYCHIATRY Early Intervention in Psychiatry Pub Date : 2025-01-01 Epub Date: 2024-12-09 DOI:10.1111/eip.13633
Julia Pfluger, James B Green, Wenhui Qi, Claire Goods, Joey Rodriguez, Michelle L West, Matcheri Keshavan, Michelle Friedman-Yakoobian
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引用次数: 0

摘要

背景:有精神病症状的个体有自杀意念和企图的风险较高。临床精神病高危患者(chrp)自杀意念和企图的患病率及相关因素尚不清楚。本研究报告了一个临床chrp样本中自杀意念和企图的患病率和临床相关因素。方法:参与者(n = 135)包括在2017年至2022年间参加临床评估的chrp - p社区专科诊所的chrp患者。评估测量了减轻的精神病症状、自杀意念和企图、临床协变量和功能。频率分析评估了终生自杀意念和企图的患病率,并进行了t检验和卡方检验,确定了临床相关性。逻辑回归评估了显著临床相关性与终生自杀企图之间的关系。结果:65%的chrp参与者认可终身自杀意念,而22.2%的参与者报告至少一次终身自杀企图。终生自杀意念的相关因素包括自我报告的性别膨胀认同、绝望、抑郁、创伤、强迫症状、洞察力:反思、创伤诊断、情绪障碍诊断和感知异常/幻觉。终生自杀企图的显著相关因素包括自我报告的绝望、抑郁、创伤诊断和情绪障碍诊断。结论:与一般人群相比,chrp患者有更高的自杀意念和企图的风险。自杀意念和企图的相关因素在诊断上可能存在异质性,因此干预措施应根据具体的临床需要进行调整。被诊断为创伤障碍的病人可能有最高的自杀意念和企图。需要持续的干预和纵向研究来澄清因果危险因素,并建立基于证据的治疗方法来治疗chrp患者的自杀意念和企图。
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Prevalence and Clinical Correlates of Suicidal Ideation and Attempts in Individuals at Clinical High Risk for Psychosis.

Background: Individuals with psychosis symptoms are at high risk for suicidal ideation and attempts. The prevalence and correlates of suicidal ideation and attempts in clinical high risk for psychosis (CHR-P) have yet to be clarified. This study reports on the prevalence and clinical correlates of suicidal ideation and attempts in a clinical CHR-P sample.

Method: Participants (n = 135) included CHR-P clients at a CHR-P community specialty clinic, who participated in a clinical assessment between 2017 and 2022. Assessments measured attenuated psychosis symptoms, suicidal ideation and attempts, clinical covariates, and functioning. Frequency analyses assessed the prevalence of lifetime suicidal ideation and attempts and t-test and Chi-square identified clinical correlates. Logistic regression assessed the relationship between significant clinical correlates and lifetime suicide attempts.

Results: Sixty-five percent of participants at CHR-P endorsed lifetime suicidal ideation, while 22.2% reported at least one lifetime attempt. Correlates for lifetime suicidal ideation included self-reported gender expansive identity, hopelessness, depression, trauma, obsessive compulsive symptoms, insight: reflectiveness, trauma diagnoses, mood disorder diagnoses, and perceptual abnormalities/hallucinations. Significant correlates for lifetime suicide attempts included self-reported hopelessness, depression, trauma diagnosis and mood disorder diagnosis.

Conclusion: CHR-P clients are at a higher risk for suicidal ideation and attempts compared to the general population. Correlates of suicidal ideation and attempts may be diagnostically heterogeneous and therefore interventions should be tailored to specific clinical needs. Clients with trauma-disorder diagnoses may be at highest risk for suicidal ideation and attempts. Continued intervention and longitudinal research is needed to clarify causal risk factors and establish evidence-based treatments for suicidal ideation and attempts in CHR-P.

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来源期刊
Early Intervention in Psychiatry
Early Intervention in Psychiatry 医学-精神病学
CiteScore
4.80
自引率
5.00%
发文量
112
审稿时长
6-12 weeks
期刊介绍: Early Intervention in Psychiatry publishes original research articles and reviews dealing with the early recognition, diagnosis and treatment across the full range of mental and substance use disorders, as well as the underlying epidemiological, biological, psychological and social mechanisms that influence the onset and early course of these disorders. The journal provides comprehensive coverage of early intervention for the full range of psychiatric disorders and mental health problems, including schizophrenia and other psychoses, mood and anxiety disorders, substance use disorders, eating disorders and personality disorders. Papers in any of the following fields are considered: diagnostic issues, psychopathology, clinical epidemiology, biological mechanisms, treatments and other forms of intervention, clinical trials, health services and economic research and mental health policy. Special features are also published, including hypotheses, controversies and snapshots of innovative service models.
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