Mina Latifian , Ehsan Mostafavi , Mohammad Ali Broumand , Fahimeh Bagheri Amiri , Mohammad Reza Mohammadi , Saber Esmaeili
{"title":"伊朗心内膜炎患者心脏瓣膜标本中伯纳蒂克氏杆菌和巴尔通体的分子研究。","authors":"Mina Latifian , Ehsan Mostafavi , Mohammad Ali Broumand , Fahimeh Bagheri Amiri , Mohammad Reza Mohammadi , Saber Esmaeili","doi":"10.1016/j.jiph.2024.102616","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Infective endocarditis (IE), is a medical condition that threatens human health. The aim of this study is the molecular investigation of <em>Coxiella burnetii</em> and <em>Bartonella</em> spp. in heart valves in Iran.</div></div><div><h3>Methods</h3><div>In this study, 146 patients with pathological evidence of IE and underwent heart valve surgery between 2016 and 2020 were selected. Furthermore, positive samples for <em>C. burnetii</em> were genotyped by the Multi Spacers Typing (MST) method, and positive samples for <em>Bartonella</em> were sequenced on the 16SrRNA gene.</div></div><div><h3>Results</h3><div>12 patients (8.2 %) were identified as positive cases of <em>C. burnetii</em>, and two novel genotypes of <em>C. burnetii</em> were identified using MST genotyping. Additionally, 15 patients (10.3 %) were diagnosed with <em>Bartonella</em> endocarditis, and all positive cases were identified as <em>Bartonella quintana</em>.</div></div><div><h3>Conclusion</h3><div>According to the identification of positive cases of Q fever endocarditis and <em>Bartonella</em> endocarditis, future studies in this field are suggested to focus on elucidating methods of prevention, diagnosis and treatment.</div></div>","PeriodicalId":16087,"journal":{"name":"Journal of Infection and Public Health","volume":"18 1","pages":"Article 102616"},"PeriodicalIF":4.7000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Molecular investigation of Coxiella burnetii and Bartonella in heart valve specimens of patients with endocarditis in Iran\",\"authors\":\"Mina Latifian , Ehsan Mostafavi , Mohammad Ali Broumand , Fahimeh Bagheri Amiri , Mohammad Reza Mohammadi , Saber Esmaeili\",\"doi\":\"10.1016/j.jiph.2024.102616\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Infective endocarditis (IE), is a medical condition that threatens human health. The aim of this study is the molecular investigation of <em>Coxiella burnetii</em> and <em>Bartonella</em> spp. in heart valves in Iran.</div></div><div><h3>Methods</h3><div>In this study, 146 patients with pathological evidence of IE and underwent heart valve surgery between 2016 and 2020 were selected. Furthermore, positive samples for <em>C. burnetii</em> were genotyped by the Multi Spacers Typing (MST) method, and positive samples for <em>Bartonella</em> were sequenced on the 16SrRNA gene.</div></div><div><h3>Results</h3><div>12 patients (8.2 %) were identified as positive cases of <em>C. burnetii</em>, and two novel genotypes of <em>C. burnetii</em> were identified using MST genotyping. Additionally, 15 patients (10.3 %) were diagnosed with <em>Bartonella</em> endocarditis, and all positive cases were identified as <em>Bartonella quintana</em>.</div></div><div><h3>Conclusion</h3><div>According to the identification of positive cases of Q fever endocarditis and <em>Bartonella</em> endocarditis, future studies in this field are suggested to focus on elucidating methods of prevention, diagnosis and treatment.</div></div>\",\"PeriodicalId\":16087,\"journal\":{\"name\":\"Journal of Infection and Public Health\",\"volume\":\"18 1\",\"pages\":\"Article 102616\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Infection and Public Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1876034124003502\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infection and Public Health","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1876034124003502","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Molecular investigation of Coxiella burnetii and Bartonella in heart valve specimens of patients with endocarditis in Iran
Background
Infective endocarditis (IE), is a medical condition that threatens human health. The aim of this study is the molecular investigation of Coxiella burnetii and Bartonella spp. in heart valves in Iran.
Methods
In this study, 146 patients with pathological evidence of IE and underwent heart valve surgery between 2016 and 2020 were selected. Furthermore, positive samples for C. burnetii were genotyped by the Multi Spacers Typing (MST) method, and positive samples for Bartonella were sequenced on the 16SrRNA gene.
Results
12 patients (8.2 %) were identified as positive cases of C. burnetii, and two novel genotypes of C. burnetii were identified using MST genotyping. Additionally, 15 patients (10.3 %) were diagnosed with Bartonella endocarditis, and all positive cases were identified as Bartonella quintana.
Conclusion
According to the identification of positive cases of Q fever endocarditis and Bartonella endocarditis, future studies in this field are suggested to focus on elucidating methods of prevention, diagnosis and treatment.
期刊介绍：
The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other.
The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners.
It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.
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