为标准三肢导联心电图服自制具有三维多通道结构的皮肤电极模板。

IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Microsystems & Nanoengineering Pub Date : 2024-12-16 DOI:10.1038/s41378-024-00838-7
Wentao Wang, Longsheng Lu, Huan Ma, Zehong Li, Xiaoyu Lu, Yingxi Xie
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引用次数: 0

摘要

可穿戴心电图(ECG)设备是诊断各种心血管疾病的主流技术,其中柔软、灵活、可渗透的电极是人机界面捕捉生物电信号的关键环节。在此,我们提出了一种自模板策略来制造银涂层纤维/硅树脂(AgCF-S)电极。通过简单的溶解-固化-再溶解过程,AgCF 内核周围的聚醋酸乙烯外壳被原位去除,形成三维(3D)多通道结构。导电纤维相互重叠,以网络状态穿过硅衬底,因此电极可以弯曲到 180° 或拉伸到 30%。AgCF-S 粘合剂中的三维多通道进一步与桐木设计结构的柔性基板相结合,在不牺牲透气性的情况下保持了高柔性,使水蒸发率达到 1.8 μg/mm2/min,且在猪皮上附着 24 小时后不会过敏。结合自主开发的标准三肢导联心电图服,可通过蓝牙实时传输高信噪比(SNR)和低方差(σ2)的多导联信号,并在客户端显示。我们的心电图设备可检测出冠心病、心律失常、心肌梗塞等典型心脏病,为未来的医疗电子技术带来了巨大前景。
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Self-template manufacturing of on-skin electrodes with 3D multi-channel structure for standard 3-limb-lead ECG suit.

Wearable electrocardiogram (ECG) devices are the mainstream technology in the diagnosis of various cardiovascular diseases, in which soft, flexible, permeable electrodes are the key link in human-machine interface to capture bioelectrical signals. Herein, we propose a self-template strategy to fabricate silver-coated fiber/silicone (AgCF-S) electrodes. With a simple dissolving-curing-redissolving process, the polyvinyl acetate shell around the AgCF core is in-situ removed to form a three-dimensional (3D) multi-channel structure. The conductive fibers overlap each other and pass through the silicon substrate in a network state, so that the electrode can be bent to 180° or stretched to 30%. The 3D multi-channels in AgCF-S adhesive is further coupled with a Kirigami-design structure of flexible substrate, to maintain high flexibility without sacrificing air-permeability, enabling an excellent water evaporation rate of 1.8 μg/mm2/min, and non-allergenic adhere on pigskin after 24 h. Combined with the self-developed standard 3-limb-lead ECG suit, multi-lead signals with high signal-to-noise ratio (SNR) and low variance (σ2), can be transmitted in real-time via Bluetooth and displayed in the client. Typical heart diseases such as coronary, arrhythmia, myocardial infarction, etc., are detected by our ECG equipment, revealing a huge promise in future medical electronics.

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来源期刊
Microsystems & Nanoengineering
Microsystems & Nanoengineering Materials Science-Materials Science (miscellaneous)
CiteScore
12.00
自引率
3.80%
发文量
123
审稿时长
20 weeks
期刊介绍: Microsystems & Nanoengineering is a comprehensive online journal that focuses on the field of Micro and Nano Electro Mechanical Systems (MEMS and NEMS). It provides a platform for researchers to share their original research findings and review articles in this area. The journal covers a wide range of topics, from fundamental research to practical applications. Published by Springer Nature, in collaboration with the Aerospace Information Research Institute, Chinese Academy of Sciences, and with the support of the State Key Laboratory of Transducer Technology, it is an esteemed publication in the field. As an open access journal, it offers free access to its content, allowing readers from around the world to benefit from the latest developments in MEMS and NEMS.
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