急性右心室流出道感染性心内膜炎的介入治疗:通往手术或经皮肺瓣膜置换术的桥梁。

IF 2.1 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Catheterization and Cardiovascular Interventions Pub Date : 2024-12-18 DOI:10.1002/ccd.31348
Alessia Callegari, Mathieu Albertini, Guillaume Reverdito, Damien Bonnet, Sophie Malekzadeh-Milani
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引用次数: 0

摘要

背景:感染性心内膜炎(IE)给经皮肺动脉瓣植入术(PPVI)或手术置换术(PVR)带来了巨大风险。目的:本研究评估了紧急经皮治疗在稳定严重右室功能障碍或梗阻性心脏休克患者方面的有效性,以便延迟手术或经皮瓣膜置换术:这项回顾性研究对 16 名右侧 IE 患者(年龄 19.9 [15.1-43.3] 岁)进行了初步经皮介入治疗。收集的数据包括心脏诊断、瓣膜类型、确定的病原体、手术细节和结果:基本诊断包括罗斯手术后主动脉瓣狭窄(43%)、修复的法洛四联症(25%)、共同动脉干(18%)和修复的双出口右心室(14%)。瓣膜类型各不相同,其中以 Contegra Ven-Pro 瓣膜(56%)和 Melody 瓣膜(25%)最为常见。IE诊断发生在上次介入/手术后66.5(28.3-87.4)个月,诊断后2(1-17)天进行了紧急经皮治疗。临床表现包括阻塞性心脏休克(50%)和脓毒性休克(25%)。干预前的 RVOT 速度为 4.4 (4.2-5) m/s,68% 的患者 RV 功能严重减退。干预措施包括球囊扩张、无盖或有盖支架植入和美乐迪瓣膜植入。所有患者的 RVOT 梗阻均立即得到了缓解,RV 收缩压显著降低(平均降低 42.0(30.2-50.0)mmHg),RV 功能也得到了改善。无围手术期死亡病例,但出现了一起并发症。随访包括手术修复(68%)和 PPVI(18%)。死亡率包括一次IE复发和一次手术死亡:结论:紧急经皮介入治疗可以稳定因IE导致RVOT阻塞的患者,从而延迟手术或经皮介入治疗。
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Interventional Treatment of Acute Right Ventricular Outflow Tract Infectious Endocarditis: A Bridge to Surgical or Percutaneous Pulmonary Valve Replacement

Background

Infective endocarditis (IE) poses significant risks following percutaneous pulmonary valve implantation (PPVI) or surgical replacement (PVR).

Aims

This study evaluates the effectiveness of emergency percutaneous treatment in stabilizing patients with severe right ventricular dysfunction or obstructive cardiac shock, allowing for delayed surgical or percutaneous valve replacement.

Methods

This retrospective study examines 16 patients (age 19.9 [15.1–43.3] years) with right-sided IE treated with primary percutaneous intervention. Data collected included cardiac diagnosis, valve types, pathogens identified, procedural details, and outcomes.

Results

Underlying diagnoses included aortic valve stenosis post-Ross surgery (43%), repaired tetralogy of Fallot (25%), common arterial trunk (18%), and repaired double outlet right ventricle (14%). Valve types varied, with Contegra Ven-Pro (56%) and Melody-valve (25%) being the most common. Diagnosis of IE occurred 66.5 (28.3–87.4) months postlast intervention/surgery, with emergency percutaneous treatment performed 2 (1–17) days postdiagnosis. Clinical presentations included obstructive cardiac shock (50%) and septic shock (25%). Preintervention RVOT velocity was 4.4 (4.2–5) m/s, with severely reduced RV function in 68%. Interventions included balloon dilatation, uncovered or covered stent implantation, and Melody valve implantation. Immediate resolution of RVOT obstruction was achieved in all patients, with significant reductions in RV systolic pressures (mean reduction 42.0 (30.2–50.0) mmHg) and improved RV function. No periprocedural deaths occurred, but one complication was noted. Follow-up included surgical repair (68%) and PPVI (18%). Mortality included one IE relapse and one surgical death.

Conclusions

Emergency percutaneous interventions can stabilize patients with RVOT obstruction due to IE, enabling delayed surgical or percutaneous interventions.

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来源期刊
CiteScore
5.40
自引率
8.70%
发文量
419
审稿时长
2 months
期刊介绍: Catheterization and Cardiovascular Interventions is an international journal covering the broad field of cardiovascular diseases. Subject material includes basic and clinical information that is derived from or related to invasive and interventional coronary or peripheral vascular techniques. The journal focuses on material that will be of immediate practical value to physicians providing patient care in the clinical laboratory setting. To accomplish this, the journal publishes Preliminary Reports and Work In Progress articles that complement the traditional Original Studies, Case Reports, and Comprehensive Reviews. Perspective and insight concerning controversial subjects and evolving technologies are provided regularly through Editorial Commentaries furnished by members of the Editorial Board and other experts. Articles are subject to double-blind peer review and complete editorial evaluation prior to any decision regarding acceptability.
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