耶鲁大学皮肤病学对皮肤t细胞淋巴瘤的看法：对新兴疗法的历史反思。

IF 2.3 4区医学 Q2 DERMATOLOGY Clinics in dermatology Pub Date : 2024-12-16 DOI:10.1016/j.clindermatol.2024.12.006

Madisen A Swallow, Richard Edelson, Michael Girardi

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引用次数: 0

摘要

皮肤T细胞淋巴瘤（CTCL）是一种非霍奇金淋巴瘤，可累及皮肤、淋巴结和血液。CTCL的两种最常见亚型是蕈样真菌病和ssamzary综合征。自1806年Jean-Louis Alibert博士首次描述蕈样真菌病以来，我们对CTCL的发病机制、临床和组织学变异以及不断发展的治疗前景的理解取得了重大进展。这个故事的主要贡献者之一是耶鲁大学医学院皮肤病学前副主席欧文·布雷弗曼博士。在此，我们向他的发现、教学、指导和临床护理致敬，这些影响了我们对CTCL的认识，以及对这种具有挑战性的恶性肿瘤的新兴治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Yale Dermatology Perspective on Cutaneous T-Cell Lymphoma: Historical Reflection to Emerging Therapies.

Cutaneous T cell lymphoma (CTCL) is a form of non-Hodgkin lymphoma that can involve the skin, along with lymph nodes and blood. The two most common subtypes of CTCL are mycosis fungoides and Sézary syndrome, Since the initial description of mycosis fungoides by Dr. Jean-Louis Alibert in 1806, there have been significant advances in our understanding of the pathogenesis of CTCL, its diverse clinical and histologic variants, and the evolving treatment landscape. One major contributor to this story has been Dr. Irwin Braverman, former Vice Chair of Dermatology at Yale School of Medicine. Herein, we provide tribute to his discoveries, teaching, mentorship, and clinical care that have influenced our insights into CTCL as well as emerging treatments for this challenging malignancy.

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来源期刊

Clinics in dermatology 医学-皮肤病学

CiteScore

4.60

自引率

7.40%

发文量

106

审稿时长

3 days

期刊介绍： Clinics in Dermatology brings you the most practical and comprehensive information on the treatment and care of skin disorders. Each issue features a Guest Editor and is devoted to a single timely topic relating to clinical dermatology. Clinics in Dermatology provides information that is... • Clinically oriented -- from evaluation to treatment, Clinics in Dermatology covers what is most relevant to you in your practice. • Authoritative -- world-renowned experts in the field assure the high-quality and currency of each issue by reporting on their areas of expertise. • Well-illustrated -- each issue is complete with photos, drawings and diagrams to illustrate points and demonstrate techniques.