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The Ethical and Practical Issues of Guiding Uninsured Patients with Skin Cancer to Resources that Alleviate Financial Burden. 引导未参保皮肤癌患者寻找减轻经济负担资源的伦理与实践问题。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-16 DOI: 10.1016/j.clindermatol.2025.01.003
Ishani Rao Dhamsania, Albert E Zhou, Neelesh Patrick Jain, Jane M Grant-Kels

A skin cancer diagnosis imposes not only a psychosocial burden but also significant financial stress due to treatment costs. This stress can intensify dramatically for patients who suddenly lose health insurance coverage, especially considering that uninsured patients are more likely to experience late-stage melanoma diagnoses and face a higher overall incidence of skin cancer than the general population. Dermatology clinics and physicians serving uninsured and vulnerable populations should be equipped with resources and strategies to ensure these patients receive adequate and timely care. We explore the ethical and actual challenges uninsured patients encounter in accessing dermatologic care for skin cancer and offer practical solutions to address and mitigate these barriers.

皮肤癌诊断不仅会造成心理社会负担,而且由于治疗费用也会带来巨大的经济压力。对于突然失去医疗保险的患者来说,这种压力可能会急剧加剧,特别是考虑到没有保险的患者更有可能经历晚期黑色素瘤诊断,并且比一般人群面临更高的皮肤癌总体发病率。为无保险和弱势人群服务的皮肤科诊所和医生应配备资源和策略,以确保这些患者得到充分和及时的护理。我们探讨了没有保险的患者在获得皮肤癌皮肤科护理时遇到的道德和实际挑战,并提供切实可行的解决方案来解决和减轻这些障碍。
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引用次数: 0
John the Baptist in Leonardo Da Vinci's Painting - What's in a Smile? 达芬奇画作中的施洗约翰——微笑意味着什么?
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-10 DOI: 10.1016/j.clindermatol.2025.01.002
Uwe Wollina, Leonard J Hoenig, Lawrence Charles Parish, Samantha E Pierce

The smile is a complex human facial expression, most commonly associated with joy. We present a detailed view on Leonardo Da Vinci's painting of Saint John the Baptist, between 1516 to 1516, which illustrates a smiling saint, which has evoked multiple explanations and theories. Discussing Da Vinci's concept of painting as science media and the two merely contradictory painting techniques chiaroscuro and sfumato, we attempt to approach this picture. Chiaroscuro is describing the strong contrasts between light and shadow, while sfumato represents another painting technique for softening the transition between colors. In the context of the positioning of John in the space, the closed smile shown in the picture, is possibly an expression of facing the Sacred.

微笑是一种复杂的人类面部表情,通常与喜悦有关。我们详细介绍了列奥纳多·达·芬奇在1516年至1516年间创作的《施洗者圣约翰》,这幅画描绘了一位微笑的圣徒,这幅画引发了多种解释和理论。通过讨论达芬奇的绘画作为科学媒介的概念,以及明暗和模糊这两种纯粹矛盾的绘画技巧,我们试图接近这幅画。明暗对比法描述的是光与影之间的强烈对比,而模糊技法则代表了另一种软化颜色之间过渡的绘画技巧。在John在空间中的定位语境下,画面中所呈现的闭合的微笑,可能是一种面对神圣的表情。
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引用次数: 0
The Art of Dermatology: Lessons Learned from Master Morphologist, Dr. Irwin Braverman. 皮肤病学的艺术:从形态学大师欧文·布雷弗曼博士那里学到的经验。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-06 DOI: 10.1016/j.clindermatol.2024.12.012
Anna Eisenstein, Margaret Johnston, Mary Laird, Sara Perkins, Jacob Siegel, Kalman Watsky

In dermatology, the art and skill of morphologic assessment is key to generating logical differential diagnoses and understanding disease pathogenesis. Dr. Irwin M. Braverman, Professor Emeritus of Dermatology at the Yale School of Medicine, is a master morphologist and his book, Skin Signs of Systemic Disease, provided key insights into the relationships between cutaneous lesions and internal disease. In an interview with Dr. Braverman, he stressed the importance morphology plays in how dermatologists diagnosis skin disorders. From Dr. Braverman, we learned an approach to the study of morphology through the lens of an art connoisseur, in addition to how to appreciate subtle clues that suggest a diagnosis and how examination of the skin brings us closer to understanding our patient, what ails them, and how we can heal them.

在皮肤病学中,形态评估的艺术和技巧是产生逻辑鉴别诊断和了解疾病发病机制的关键。Irwin M. Braverman博士是耶鲁大学医学院皮肤病学荣誉教授,是一位形态学大师,他的著作《全身疾病的皮肤体征》为皮肤病变和内部疾病之间的关系提供了关键的见解。在接受布雷弗曼博士的采访时,他强调了形态学在皮肤科医生诊断皮肤病中的重要性。从布雷弗曼博士那里,我们学到了一种通过艺术鉴赏家的视角来研究形态学的方法,此外,我们还学会了如何欣赏暗示诊断的细微线索,以及如何通过皮肤检查让我们更接近了解病人,了解他们的病痛,以及如何治愈他们。
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引用次数: 0
Bipolar disorder in patients with psoriasis, and the impact of lithium therapy on psoriasis. 双相情感障碍的牛皮癣患者,以及锂治疗对牛皮癣的影响。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-04 DOI: 10.1016/j.clindermatol.2025.01.001
Caroline Stamu-O'Brien, Megan Hoang, Ioanna Papoutsi, Cemre Busra Turk, Anupam Das, George Kroumpouzos

There is a significant amount of research examining the link between psoriasis and common mental health disorders; however, studies on less common psychiatric disorders, such as bipolar disorder (BD), remain limited. We conducted a systematic review of studies in the PubMed and Cochrane databases that explored the relationship between BD and psoriasis. Additionally, we evaluated the impact of lithium on psoriasis in patients with BD and included a quality assessment of all the studies. This review covers five studies that addressed the connection between psoriasis and psychiatric disorders, three studies on medical conditions in patients with BD, and four studies examining the effects of lithium intake on psoriasis in BD patients. We found substantial evidence supporting a link between psoriasis and BD, suggesting that psoriasis is an independent risk factor for BD. Patients with psoriasis are also more likely to use psychotropic medications. A limited number of studies indicate that lithium therapy may trigger or worsen psoriasis. We also explore the mechanisms of lithium-induced or -aggravated psoriasis, highlighting the intricate interplay between lithium treatment, inositol depletion, and psoriasis in patients with BD. In a placebo-controlled, randomized study, inositol supplementation could mitigate psoriasis in patients taking lithium. Additional research is needed to evaluate the efficacy of inositol supplementation for patients with psoriasis who need to continue lithium treatment for their BD.

有大量的研究调查了牛皮癣和常见精神疾病之间的联系;然而,对不太常见的精神疾病,如双相情感障碍(BD)的研究仍然有限。我们对PubMed和Cochrane数据库中的研究进行了系统回顾,探讨双相障碍和牛皮癣之间的关系。此外,我们评估了锂对双相障碍患者银屑病的影响,并纳入了所有研究的质量评估。这篇综述涵盖了5项关于牛皮癣和精神疾病之间关系的研究,3项关于双相障碍患者医疗状况的研究,以及4项关于锂摄入对双相障碍患者牛皮癣影响的研究。我们发现大量证据支持牛皮癣和双相障碍之间的联系,表明牛皮癣是双相障碍的独立危险因素。牛皮癣患者也更有可能使用精神药物。有限数量的研究表明,锂治疗可能引发或加重牛皮癣。我们还探讨了锂诱导或加重牛皮癣的机制,强调了锂治疗、肌醇消耗和BD患者牛皮癣之间复杂的相互作用。在一项安慰剂对照的随机研究中,补充肌醇可以减轻服用锂的患者的牛皮癣。牛皮癣是一种慢性炎症性皮肤病,影响全球2-3%的人口,需要进一步的研究来评估补充肌醇对需要继续锂治疗的牛皮癣患者的疗效其特征是异常的免疫反应,涉及树突状细胞、辅助性T细胞(Th)1/Th17淋巴细胞和角质形成细胞,每种细胞都参与病理相互作用,导致由细胞因子环境介导的全身效应,而不是皮肤变化。银屑病对患者的生活质量有显著影响牛皮癣患者,特别是严重形式的牛皮癣患者,会经历许多合并症,包括精神疾病。5-15牛皮癣患者患各种精神疾病的风险增加,包括抑郁和焦虑,13,16可能与影响神经精神途径的炎症细胞因子负担增加有关。13,17牛皮癣的可见影响也可能导致显著的压力,降低自尊和耻辱,进一步导致不良的精神结果关于牛皮癣与常见精神障碍(如重度抑郁症)之间的联系,有大量的研究。3,13,14不太常见的精神疾病,如双相情感障碍(BD),12,15,16的研究仍然有限。双相障碍影响全球约1-3%的人口,其特征是抑郁和躁狂(或轻躁狂)交替发作。它会导致情绪和能量水平的显著变化,导致个人、社会和职业功能的严重损害。锂是一种公认的双相障碍治疗方法,对控制急性躁狂和维持情绪稳定有效。锂具有稳定情绪、抗躁狂、抗抑郁和抗自杀的特性;然而,它的使用往往会使问题复杂化,因为它可能引发或加重牛皮癣,这反过来又显著地导致了锂治疗的不依从性锂影响银屑病的机制尚不清楚,关于接受锂治疗的双相障碍患者银屑病的研究文献有限。
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引用次数: 0
Drug-induced Hypersensitivity Syndrome after COVID-19 Vaccination. COVID-19疫苗接种后药物致过敏综合征
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-03 DOI: 10.1016/j.clindermatol.2024.12.021
Henry Zou, Steven Daveluy
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引用次数: 0
The portrayal of moles in dermatology cartoons. 皮肤病学漫画中痣的形象。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-01-03 DOI: 10.1016/j.clindermatol.2024.12.022
Sophie Walter

Media portrayals of medical disorders can influence public beliefs about those disorders. There have been no previous studies about the depiction of dermatological conditions in cartoons. The aim of this study was to describe the portrayal of skin moles in cartoons. The image sections of internet search engines Google, Yahoo, Bing and DuckDuckGo were inspected for single-panel cartoons which referred to skin moles. Each cartoon was examined according to characteristics of the patient, mole(s) and treatment. Sixty-six cartoons were identified. One third of the moles were portrayed as suspicious, a quality often conveyed by a furtive-looking mole creature on the patient. Most cartoons depicted or mentioned a medical doctor; a dermatologist featured in 12 cases. There was discretion in how the moles were managed. Among the treatment options were excision, hitting the mole with a mallet, and observation over time. It was noteworthy that none of the cartoons made specific reference to melanoma. The study findings may creatively inform efforts to educate the public and health professionals about moles and their management.

媒体对医学疾病的描述会影响公众对这些疾病的看法。此前还没有关于漫画中皮肤病描述的研究。这项研究的目的是描述漫画中皮肤痣的形象。互联网搜索引擎b谷歌、雅虎、必应和DuckDuckGo的图像部分被检查了有关皮肤痣的单面板漫画。根据患者的特征、痣和治疗方法对每张卡通进行检查。确定了66幅漫画。三分之一的痣被描绘成可疑的,这种特征通常由看起来鬼鬼祟祟的痣生物在病人身上传达出来。大多数漫画描绘或提到了医生;一位皮肤科医生记录了12例病例。管理鼹鼠的方式很谨慎。治疗方案包括切除,用木槌击打痣,并观察一段时间。值得注意的是,这些漫画都没有特别提到黑色素瘤。研究结果可能创造性地为教育公众和卫生专业人员关于痣及其管理的努力提供信息。
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引用次数: 0
Navigating the Ethics of Predatory Journals and Processing Fees in Dermatology. 在皮肤病学掠夺性期刊和处理费用的伦理导航。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-12-27 DOI: 10.1016/j.clindermatol.2024.12.019
Sowmya Ravi, Albert E Zhou, Brett Sloan, Lionel Bercovitch, Jane M Grant-Kels

The rise of predatory journals has created a pressing ethical dilemma in academic publishing, exploiting researchers' urgency to publish while prioritizing profits over quality. These journals, characterized by deceptive practices and inadequate peer review, often undermine scientific integrity and disproportionately affect early-career academicians and those from underfunded institutions. While open-access publishing aims to democratize knowledge, its reliance on high processing charges (APCs) poses accessibility challenges, particularly in resource-limited settings. This issue extends beyond predatory journals, as even reputable journals often impose substantial APCs, creating a broader crisis of inequitable access to publishing research findings. The implications of these exploitative practices are far-reaching, potentially compromising patient care (via publication of inferior papers in predatory journals), fostering researcher burnout, and hindering global collaboration. Addressing this requires systemic reform, including increased transparency, reduced costs, expanded funding, and promoting community-led publishing platforms. Ethical publishing practices must prioritize inclusivity and the dissemination of knowledge to preserve the integrity and accessibility of academic research.

掠夺性期刊的兴起给学术出版带来了一个紧迫的伦理困境,它们利用了研究人员发表论文的紧迫性,同时将利润置于质量之上。这些期刊的特点是欺骗行为和同行评议不足,经常破坏科学诚信,不成比例地影响到职业生涯早期的院士和资金不足的机构的院士。虽然开放获取出版的目标是使知识民主化,但它对高昂的处理费用(apc)的依赖带来了可及性挑战,特别是在资源有限的环境中。这个问题超出了掠夺性期刊的范畴,因为即使是声誉良好的期刊也经常施加大量的apc,从而造成更广泛的不公平获取发表研究成果的危机。这些剥削行为的影响是深远的,可能危及患者护理(通过在掠夺性期刊上发表劣质论文),促进研究人员倦怠,阻碍全球合作。解决这一问题需要进行系统性改革,包括提高透明度、降低成本、扩大资金投入和促进社区主导的出版平台。道德出版实践必须优先考虑包容性和知识传播,以保持学术研究的完整性和可及性。
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引用次数: 0
Biopsy Quotas: Ethical Implications of Financial Incentives and Penalties on Dermatologic Care Providers. 活检配额:对皮肤护理提供者的经济激励和处罚的伦理含义。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-12-27 DOI: 10.1016/j.clindermatol.2024.12.020
Timothy Klufas, Ayushya Ajmani, Shannon Hanggodo, Albert E Zhou, Hao Feng, Jane M Grant-Kels

The evolution of healthcare payment models has profoundly influenced clinical practices and physician decision-making. While fee-for-service (FFS) models incentivize procedural volume, systems based on Relative Value Units (RVUs) have introduced standardized metrics to compensate physicians based on care complexity and workload. As corporations increasingly own healthcare, financial incentives such as RVUs and procedural quotas raise ethical concerns. Quotas intended to boost efficiency and profitability may prompt corporate entities to pressure clinicians to meet procedural targets, potentially prioritizing financial performance over patient welfare. Such pressures risk leading to overtreatment and unnecessary procedures, challenging the principles of non-maleficence and beneficence, especially when less invasive or non-invasive alternatives are clinically viable. Ethical frameworks, including the AMA Code of Medical Ethics, emphasize the need for compensation models that align with clinical judgment and support patient-centered care.

医疗支付模式的演变深刻地影响了临床实践和医生的决策。虽然按服务收费(FFS)模式激励了手术量,但基于相对价值单位(rvu)的系统引入了标准化指标,根据护理复杂性和工作量对医生进行补偿。随着企业越来越多地拥有医疗保健,rvu和程序配额等财务激励措施引发了道德问题。旨在提高效率和盈利能力的配额可能促使公司实体向临床医生施压,要求他们达到程序性目标,潜在地将财务绩效置于患者福利之上。这种压力可能导致过度治疗和不必要的手术,挑战了无害和有益的原则,特别是当临床可行的微创或非侵入性替代方案时。伦理框架,包括美国医学协会医学伦理准则,强调需要与临床判断一致的补偿模式,并支持以患者为中心的护理。
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引用次数: 0
Psoriasis: Perspectives from Irwin M. Braverman, MD. 牛皮癣:欧文M.布雷弗曼医学博士的观点。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-12-21 DOI: 10.1016/j.clindermatol.2024.12.016
Jeffrey M Cohen, Christopher G Bunick

Dr. Irwin M. Braverman is recognized as an expert on many skin diseases including psoriasis, an immune-mediated disorder that presents with scaly erythematous plaques. The most common clinical subtype is plaque psoriasis, with scalp, inverse, guttate, pustular, and nail psoriasis representing additional subtypes. Psoriasis has been associated with several comorbidities, particularly psoriatic arthritis, which affects up to 30% of those with psoriasis. Psoriasis can have an enormous impact on patients, and Dr. Braverman reflects that "it is hard to think of another disease that can be so destructive or impactful." Over the course of his career, Dr. Braverman treated many patients with psoriasis and observed several significant therapeutic advances, including the widespread use of psoralens with ultraviolet A phototherapy (PUVA) and the introduction of methotrexate. He also contributed to research on the pathophysiology of psoriasis, studying the hallmark dilated capillary loops. Ultimately, Dr. Braverman believes that "taking care of a patient with psoriasis goes into the making of a dermatologist."

Irwin M. Braverman博士是许多皮肤病的公认专家,包括牛皮癣,一种免疫介导的疾病,呈现鳞状红斑斑块。最常见的临床亚型是斑块型银屑病,另外还有头皮型、逆型、点滴型、脓疱型和指甲型银屑病。银屑病与几种合并症有关,特别是银屑病关节炎,影响高达30%的银屑病患者。牛皮癣会对患者产生巨大的影响,布雷弗曼博士认为,“很难想象还有其他疾病会如此具有破坏性或影响。”在他的职业生涯中,Braverman博士治疗了许多牛皮癣患者,并观察到一些重要的治疗进展,包括广泛使用补骨脂素与紫外线A光疗(PUVA)和引入甲氨蝶呤。他还对银屑病的病理生理学研究做出了贡献,研究了标志性的毛细血管袢扩张。最终,布雷弗曼博士认为,“照顾牛皮癣患者是皮肤科医生的必要条件。”
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引用次数: 0
Gender Representation and Leadership Dynamics at the American Academy of Dermatology Annual Meetings: A Retrospective Observational Study. 美国皮肤病学会年会的性别代表和领导动态:一项回顾性观察研究。
IF 2.3 4区 医学 Q2 DERMATOLOGY Pub Date : 2024-12-19 DOI: 10.1016/j.clindermatol.2024.12.018
Sabrina Y Almashni, Matthew D Viveiros, Varshita Chirumamilla, Kateri L Schoettinger, Jessica A Kaffenberger
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引用次数: 0
期刊
Clinics in dermatology
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