{"title":"三例皮革制品中的 2-(硫氰基甲硫基)苯并噻唑过敏性接触性皮炎病例。","authors":"Quentin Samaran, Olivier Dereure, Nadia Raison-Peyron","doi":"10.1111/cod.14737","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>2-(Thiocyanomethylthio)benzothiazole (TCMTB) is a fungicide product widely used in the leather industry, particularly since the 1990s. However, reports of allergic contact dermatitis triggered by this chemical are scarce.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To investigate three cases of dermatitis following contact with leather products, possibly related to TCMTB.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Three female patients, aged 33–53, were referred with suspected allergic contact dermatitis related to leather products. Two patients presented with dermatitis on the feet, while one patient had dermatitis on the back and thighs. All patients were patch-tested with the European baseline series, a shoe series, TMCTB (0.1% pet), and scrapings from their personal leather products.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>All patients showed reactions to the scrapings from their personal products (+ to ++) and to TCMTB (++ to +++). Additionally, one patient was sensitised to mercapto mix and mercaptobenzothiazole (both ++), while another reacted to chromium (++), cobalt (+), 4-tert-butylphenol-formaldehyde resin (+) and colophonium (++). All patients were advised to avoid TCMTB and to be cautious with leather, synthetic leather, and varnished wood.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>If contact dermatitis related to leather exposure is suspected, patch testing with TCMTB 0.1% pet should be included, as it might be the only positive finding.</p>\n </section>\n </div>","PeriodicalId":10527,"journal":{"name":"Contact Dermatitis","volume":"92 4","pages":"299-303"},"PeriodicalIF":4.8000,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Three Cases of Allergic Contact Dermatitis to 2-(Thiocyanomethylthio)benzothiazole in Leather Items\",\"authors\":\"Quentin Samaran, Olivier Dereure, Nadia Raison-Peyron\",\"doi\":\"10.1111/cod.14737\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>2-(Thiocyanomethylthio)benzothiazole (TCMTB) is a fungicide product widely used in the leather industry, particularly since the 1990s. However, reports of allergic contact dermatitis triggered by this chemical are scarce.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To investigate three cases of dermatitis following contact with leather products, possibly related to TCMTB.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Three female patients, aged 33–53, were referred with suspected allergic contact dermatitis related to leather products. Two patients presented with dermatitis on the feet, while one patient had dermatitis on the back and thighs. All patients were patch-tested with the European baseline series, a shoe series, TMCTB (0.1% pet), and scrapings from their personal leather products.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>All patients showed reactions to the scrapings from their personal products (+ to ++) and to TCMTB (++ to +++). Additionally, one patient was sensitised to mercapto mix and mercaptobenzothiazole (both ++), while another reacted to chromium (++), cobalt (+), 4-tert-butylphenol-formaldehyde resin (+) and colophonium (++). All patients were advised to avoid TCMTB and to be cautious with leather, synthetic leather, and varnished wood.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>If contact dermatitis related to leather exposure is suspected, patch testing with TCMTB 0.1% pet should be included, as it might be the only positive finding.</p>\\n </section>\\n </div>\",\"PeriodicalId\":10527,\"journal\":{\"name\":\"Contact Dermatitis\",\"volume\":\"92 4\",\"pages\":\"299-303\"},\"PeriodicalIF\":4.8000,\"publicationDate\":\"2024-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Contact Dermatitis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cod.14737\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Contact Dermatitis","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cod.14737","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ALLERGY","Score":null,"Total":0}
Three Cases of Allergic Contact Dermatitis to 2-(Thiocyanomethylthio)benzothiazole in Leather Items
Background
2-(Thiocyanomethylthio)benzothiazole (TCMTB) is a fungicide product widely used in the leather industry, particularly since the 1990s. However, reports of allergic contact dermatitis triggered by this chemical are scarce.
Objectives
To investigate three cases of dermatitis following contact with leather products, possibly related to TCMTB.
Methods
Three female patients, aged 33–53, were referred with suspected allergic contact dermatitis related to leather products. Two patients presented with dermatitis on the feet, while one patient had dermatitis on the back and thighs. All patients were patch-tested with the European baseline series, a shoe series, TMCTB (0.1% pet), and scrapings from their personal leather products.
Results
All patients showed reactions to the scrapings from their personal products (+ to ++) and to TCMTB (++ to +++). Additionally, one patient was sensitised to mercapto mix and mercaptobenzothiazole (both ++), while another reacted to chromium (++), cobalt (+), 4-tert-butylphenol-formaldehyde resin (+) and colophonium (++). All patients were advised to avoid TCMTB and to be cautious with leather, synthetic leather, and varnished wood.
Conclusions
If contact dermatitis related to leather exposure is suspected, patch testing with TCMTB 0.1% pet should be included, as it might be the only positive finding.
期刊介绍:
Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".