Correlation between popliteal vein functional diameter and the severity of chronic venous disease.

Objective: This study measured the diameter change of the popliteal vein under a rated pressure gradient and evaluated the relationship between popliteal vein functional diameter and severity of chronic venous disease.

Methods: Ultrasound examination was performed on 173 lower limbs of 173 patients admitted from June 2023 to January 2024. The diameter of the popliteal vein was measured before and after compression with the thigh inflatable cuff. The correlation between popliteal vein functional diameter and venous clinical severity score ( VCSS ) was statistically analyzed.

Results: Venous clinical severity score values ranged from 1 to 28 (median 7). The Spearman correlation analysis between venous clinical severity score and functional diameter had an rs value of -0.222, p (double-tailed) < .001. The correlation between VCSS and popliteal vein diameter variation index yielded rs = -0.633, p (double-tailed) < .001.

Conclusion: This study found that popliteal vein functional diameter negatively correlated with the severity of chronic venous disease. Popliteal vein functional diameter and diameter variation index can be used as disease-specific indicators to quantify the severity of chronic venous disease. (Clinicaltrials.gov Identifier: NCT06175481).