Jelena Vladić , Igor Jerković , Valentina Pavić , Dragoljub Cvetković , Stela Jokić , Krunoslav Aladić , Kristian Pastor , Ana Rita C. Duarte
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引用次数: 0
摘要
本研究评估了深度共晶系统（DESs）在提高莳萝（Anethum graveolens L.）超临界提取物的化学和微生物稳定性以及抗菌活性方面的潜力，这些提取物富含香芹酮和柠檬烯，超过6个月的储存。以甜菜素为基础，测试了各种脱脂油对莳萝提取物的化学完整性和抗菌性能的影响。在储存过程中提取物顶空剖面的显著变化表明了降解反应。与对照提取物相比，莳萝-Bet/LA提取物体系（Bet/LA中的莳萝提取物）被证明是最有效的，显著减缓了降解并增强了抗菌活性。具体来说，该体系对革兰氏阴性菌的抑制效果是对照的20 - 40倍，对革兰氏阳性菌的抑制效果是对照的5 - 8倍。此外，莳萝- bet /LA体系在储存过程中也最有效地保持了抗菌效力，表明其作为延长莳萝超临界提取物的保质期和生物活性的可持续解决方案的潜力。
Exploring the potential of deep eutectic systems for the preservation of the chemical profile and antibacterial potential of dill (Anethum graveolens L.) supercritical CO₂ extracts
This study evaluated the potential of deep eutectic systems (DESs) to enhance the chemical and microbiological stability, as well as the antibacterial activity of dill (Anethum graveolens L.) supercritical extracts, rich in carvone and limonene, over six months of storage. Various betaine-based DESs were tested for their ability to preserve the chemical integrity and enhance the antibacterial properties of dill extracts. Significant alterations in the headspace profile of extracts during storage indicated degradation reactions. The dill-Bet/LA extract system (dill extract in Bet/LA) proved most effective, significantly slowing degradation and enhancing antibacterial activity compared to the dill-control extract. Specifically, this system exhibited 20–40-fold greater efficacy against Gram-negative bacteria and 5–8-fold stronger activity against Gram-positive bacteria than the dill-control. Furthermore, the dill-Bet/LA system was also the most effective in preserving antimicrobial potency during storage, demonstrating its potential as a sustainable solution for extending the shelf life and bioactivity of dill supercritical extracts.
期刊介绍：
The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics.
Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.
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