一种基于大功率二极管激光器超速工作模式的生物医学成像激光超声发射器。

IF 3.8 2区 物理与天体物理 Q1 ACOUSTICS Ultrasonics Pub Date : 2024-12-13 DOI:10.1016/j.ultras.2024.107548
Miguel Sanchez, Daniel Gallego, Alexander A Oraevsky, Horacio Lamela
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引用次数: 0

摘要

在医疗应用中用于产生超声的最常见换能器是基于应用于压电换能器和电容微机械超声换能器的短电脉冲。然而,压电换能器的带宽有限,这是由其物理厚度决定的,而电容式微机械超声换能器的传输效率很差。高频截止限制了超声图像的空间分辨率。低频截断限制了超声图像上物体的体积对比度,因此通常只显示组织边界。这些限制可以用激光产生的超声波来克服。激光超声的产生是基于光声效应的,这大大增加了超声信号的带宽。我们展示了使用在超速状态下工作的高功率二极管激光器产生超宽带超声脉冲,并在聚二甲基硅氧烷基质中使用蜡烛烟灰薄复合薄膜作为发射器。我们在-6 dB水平下实现了228.59 kPa的峰值压力和0.1 MHz至30 MHz (BW6dB≈200%)的超频带宽,光声转换效率为6.27 × 10-3 [Pa/(W/m2)]或3.35 × 106 [Pa/(mJ/cm2)]。我们提出了一种紧凑和低成本的超宽带激光超声发射器,可以调节传输频率的带宽,并能够在离体组织中产生超声图像。
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A laser ultrasound emitter based on high-power diode laser in overdrive operation mode for biomedical imaging applications.

The most common transducers used to generate ultrasound in medical applications are based on short electrical pulses applied to piezoelectric transducers and capacitive micromachined ultrasound transducers. However, piezoelectric transducers have a limited frequency bandwidth, defined by their physical thickness, and capacitive micromachined ultrasound transducers have poor transmission efficiency. The high frequency cutoff limits the spatial resolution of ultrasonic images. The low frequency cutoff limits volumetric contrast of objects on ultrasound images so that typically only tissue boundaries are displayed. These limitations can be overcome with laser generated ultrasound. Laser ultrasound generation is based on the optoacoustic effect, which greatly increases the bandwidth of ultrasound signals. We show the generation of ultra-wideband ultrasound pulses using high power diode lasers operating in the overdrive regime, and thin composite films of candle soot in polydimethylsiloxane matrix as transmitters. We achieved a peak pressure of 228.59 kPa and a ultrawive bandwidth of 0.1 MHz-to-30 MHz (BW6dB≈200%) at -6 dB level with an optoacoustic conversion efficiency of 6.27 × 10-3 [Pa/(W/m2)] or 3.35 × 106 [Pa/(mJ/cm2)]. We present a compact and low-cost ultra-wideband laser ultrasound emitter with the possibility to adjust the bandwidth of the transmitted frequency and the ability to generate ultrasonic images in ex-vivo tissues.

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来源期刊
Ultrasonics
Ultrasonics 医学-核医学
CiteScore
7.60
自引率
19.00%
发文量
186
审稿时长
3.9 months
期刊介绍: Ultrasonics is the only internationally established journal which covers the entire field of ultrasound research and technology and all its many applications. Ultrasonics contains a variety of sections to keep readers fully informed and up-to-date on the whole spectrum of research and development throughout the world. Ultrasonics publishes papers of exceptional quality and of relevance to both academia and industry. Manuscripts in which ultrasonics is a central issue and not simply an incidental tool or minor issue, are welcomed. As well as top quality original research papers and review articles by world renowned experts, Ultrasonics also regularly features short communications, a calendar of forthcoming events and special issues dedicated to topical subjects.
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