一种用于术中可视化、引导和荧光温度监测的增强现实遮阳板。

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS Journal of Biophotonics Pub Date : 2024-12-23 DOI:10.1002/jbio.202400417
Oscar Cipolato, Matthias Fauconneau, Paige J. LeValley, Robert Nißler, Benjamin Suter, Inge K. Herrmann
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引用次数: 0

摘要

荧光引导手术,包括肿瘤切除和组织焊接,通过提供增强的控制,最大限度地减少组织损伤,提高恢复和结果,正在推进手术精度的前沿。然而,将荧光可视化与实时温度监测相结合仍然是一个挑战,限制了更广泛的临床应用。我们通过增强现实(AR)遮阳板解决了这个问题,该遮阳板结合了纳米材料激发,荧光检测和温度监测。使用先进的荧光纳米颗粒,如吲哚菁绿掺杂颗粒和碳纳米管,遮阳板提供了肉眼看不见的手术场和表面下情况的全面视图。这种集成通过确保最佳温度和实时激光引导,提高了荧光引导手术(包括激光组织焊接)的安全性和有效性。所提出的技术增强了现有的外科技术,并在传统方法不足的领域支持新策略和传感技术的发展,标志着精确手术的重大进步,并有可能改善患者护理。
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An Augmented Reality Visor for Intraoperative Visualization, Guidance, and Temperature Monitoring Using Fluorescence

Fluorescence-guided surgeries, including tumor resection and tissue soldering, are advancing the frontiers of surgical precision by offering enhanced control that minimizes tissue damage, improving recovery and outcomes. However, integrating fluorescence visualization with real-time temperature monitoring remains a challenge, limiting broader clinical use. We address this issue with an augmented reality (AR) visor that combines nanomaterial excitation, fluorescence detection, and temperature monitoring. Using advanced fluorescent nanoparticles like indocyanine green-doped particles and carbon nanotubes, the visor provides a comprehensive view of both the surgical field and sub-surface conditions invisible to the naked eye. This integration improves the safety and efficacy of fluorescence-guided surgeries, including laser tissue soldering, by ensuring optimal temperatures and laser guidance in real time. The presented technology enhances existing surgical techniques and supports the development of new strategies and sensing technologies in areas where traditional methods fall short, marking significant progress in precision surgery and potentially improving patient care.

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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
期刊最新文献
Issue Information Front Cover Front Cover Issue Information A Miniaturized In Vivo Fluorescence Microscopy Method for Monitoring Circulating Tumor Cells in Freely Moving Animals
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