电磁辐射和光子发射在神经元通讯和神经退行性疾病中的作用。

IF 3.2 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Progress in Biophysics & Molecular Biology Pub Date : 2024-12-26 DOI:10.1016/j.pbiomolbio.2024.12.004
Aysin Erboz, Elif Kesekler, Pier Luigi Gentili, Vladimir N Uversky, Orkid Coskuner-Weber
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引用次数: 0

摘要

电磁辐射与神经元通讯的交叉,关注生物光子发射在脑功能和神经退行性疾病中的潜在作用是一个新兴的研究领域。传统上认为,神经元通过电化学脉冲编码和传递信息,产生可被脑电图和脑磁图检测到的电磁场。最近的发现表明,神经元也可能发射生物光子,这表明除了常规的突触相互作用外,还有一个额外的通信通道。分析了这种双重信号系统在同步神经元活动和改善信息传递方面的潜力,并对类脑计算系统产生了影响。临床相关性通过神经退行性疾病和内在失调蛋白的透镜进行探索,其中氧化应激可能改变生物光子发射,为阿尔茨海默病和帕金森病等病理条件提供线索。低水平激光治疗(LLLT)的潜在治疗用途也因其调节生物光子活性和减轻氧化应激的能力而被研究,为治疗提供了新的机会。在这里,我们邀请进一步探索电磁现象在脑功能中发挥的复杂作用,可能导致计算神经科学和神经退行性疾病的医学治疗方面的突破。
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Electromagnetic radiation and biophoton emission in neuronal communication and neurodegenerative diseases.

The intersection of electromagnetic radiation and neuronal communication, focusing on the potential role of biophoton emission in brain function and neurodegenerative diseases is an emerging research area. Traditionally, it is believed that neurons encode and communicate information via electrochemical impulses, generating electromagnetic fields detectable by EEG and MEG. Recent discoveries indicate that neurons may also emit biophotons, suggesting an additional communication channel alongside the regular synaptic interactions. This dual signaling system is analyzed for its potential in synchronizing neuronal activity and improving information transfer, with implications for brain-like computing systems. The clinical relevance is explored through the lens of neurodegenerative diseases and intrinsically disordered proteins, where oxidative stress may alter biophoton emission, offering clues for pathological conditions, such as Alzheimer's and Parkinson's diseases. The potential therapeutic use of Low-Level Laser Therapy (LLLT) is also examined for its ability to modulate biophoton activity and mitigate oxidative stress, presenting new opportunities for treatment. Here, we invite further exploration into the intricate roles the electromagnetic phenomena play in brain function, potentially leading to breakthroughs in computational neuroscience and medical therapies for neurodegenerative diseases.

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来源期刊
Progress in Biophysics & Molecular Biology
Progress in Biophysics & Molecular Biology 生物-生化与分子生物学
CiteScore
8.60
自引率
7.90%
发文量
85
审稿时长
85 days
期刊介绍: Progress in Biophysics & Molecular Biology is an international review journal and covers the ground between the physical and biological sciences since its launch in 1950. It indicates to the physicist the great variety of unsolved problems awaiting attention in biology and medicine. The biologist and biochemist will find that this journal presents new and stimulating ideas and novel approaches to studying and influencing structural and functional properties of the living organism. This journal will be of particular interest to biophysicists, biologists, biochemists, cell physiologists, systems biologists, and molecular biologists.
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