探索慢性心力衰竭患者易损期的症状群和核心症状:基于网络的分析

Zekun Bian, Bin Shang, Caifeng Luo, Fei Lv, Weiyi Sun, Yijing Gong, Jun Liu
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摘要

目的:构建弱势期慢性心力衰竭患者的症状网络,识别不同症状群之间的核心症状和桥梁症状。方法与结果:采用方便抽样的方法,选取镇江市两家三级甲等医院心内科出院后3个月内的慢性心力衰竭患者402例,采用明尼苏达州心衰患者生活问卷(MLHFQ)症状相关条目进行调查。使用R语言构建症状网络。构建的症状网络结构稳定,相关稳定系数为0.595。在该网络中,“抑郁”(MLHFQ9)、“用力时呼吸困难”(MLHFQ3)和“担忧”(MLHFQ7)是核心症状。“认知问题”(MLHFQ8)、“睡眠困难”(MLHFQ4)和“疲劳”(MLHFQ6)是连接情绪-认知和躯体症状群的桥梁症状。在网络比较检验中,不同性别、不同居住地患者的症状网络无显著差异。结论:“抑郁”和“需要休息增加”分别是慢性心力衰竭易损期的核心症状和最严重症状,“认知问题”是最重要的桥梁症状。临床护理人员可以根据核心症状和桥梁症状,重点关注情绪和认知症状群,制定精准的干预方案,以提高慢性心力衰竭患者易危期症状管理的效果。
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Exploring symptom clusters and core symptoms during the vulnerable phase in patients with chronic heart failure: a network-based analysis.

Aims: To construct a symptom network of chronic heart failure patients in the vulnerable period and identify core symptoms and bridge symptoms between different symptom clusters.

Methods and results: A convenience sampling method was used to select 402 patients with chronic heart failure within 3 months after discharge from the cardiology departments of two tertiary-level A hospitals in Zhenjiang City, and symptom-related entries of the Minnesota living with heart failure questionnaire (MLHFQ) were used to conduct the survey. Symptom networks were constructed using the R language. The constructed symptom network was structurally stable, and the correlation stability coefficient was 0.595. In the network, 'depression' (MLHFQ9), 'dyspnoea on exertion' (MLHFQ3), and 'worry' (MLHFQ7) are the core symptoms. 'Cognitive problems' (MLHFQ8), 'sleep difficulties' (MLHFQ4), and 'fatigue' (MLHFQ6) are bridge symptoms connecting the emotional-cognitive and somatic symptom clusters. In the network comparison test, there were no significant differences in symptom networks between patients of different genders and places of residence.

Conclusion: 'Depression' and 'increased need to rest' are the core and most severe symptoms, respectively, in the vulnerable phase of chronic heart failure, and 'cognitive problems' is the most important bridge symptom. Clinical caregivers can build a precise intervention programme based on the core and bridge symptoms and focus on the emotional and cognitive symptom clusters, in order to improve the efficacy of symptom management during the vulnerable period in patients with chronic heart failure.

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