雌性激素对女性肾脏保护特性的潜在细微差别。

IF 14.8 1区 医学 Q1 UROLOGY & NEPHROLOGY Kidney international Pub Date : 2025-01-01 DOI:10.1016/j.kint.2024.10.017
Lanette M. Christensen , Matthew H. Levine
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引用次数: 0

摘要

Kitai等人目前的一项研究发现,在青春期雌激素/女性性激素敏感化之前切除卵巢可防止肾脏缺血再灌注损伤,这对该领域普遍认为雌激素具有肾脏保护功能的观点提出了质疑。这些结果耐人寻味,可能具有重要的临床意义,但需要对所报告的结论进行一些澄清和证实。
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Potential nuances in renoprotective properties of estrogen in females
A current study by Kitai et al. found that ovariectomy before estrogen/female sex hormone sensitization at puberty provided protection against kidney ischemia reperfusion injury, challenging the general consensus within the field that estrogen provides renoprotective function. These results are intriguing and could have important clinical implications, while requiring some clarification and substantiation of the conclusions reported.
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来源期刊
Kidney international
Kidney international 医学-泌尿学与肾脏学
CiteScore
23.30
自引率
3.10%
发文量
490
审稿时长
3-6 weeks
期刊介绍: Kidney International (KI), the official journal of the International Society of Nephrology, is led by Dr. Pierre Ronco (Paris, France) and stands as one of nephrology's most cited and esteemed publications worldwide. KI provides exceptional benefits for both readers and authors, featuring highly cited original articles, focused reviews, cutting-edge imaging techniques, and lively discussions on controversial topics. The journal is dedicated to kidney research, serving researchers, clinical investigators, and practicing nephrologists.
期刊最新文献
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