从微观到宏观：了解B12缺乏对女性健康的深远影响。

IF 1.7 4区医学 Q2 NURSING Public Health Nursing Pub Date : 2025-01-02 DOI:10.1111/phn.13525

Betsy Sara Zacharias, Sheela Upendra, Dipali Dumbre

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引用次数: 0

摘要

背景：维生素B12 （B12）是人体必需的重要维生素，在单碳代谢中起辅酶的作用。目的：系统地回顾证据，以确定妇女B12缺乏的并发症。方法：我们对过去25年（1999-2024）发表的与女性B12缺乏症相关的定量研究进行了系统检索，使用电子数据库，如Scopus、Web of science、CINAHL、PubMed和Medline。结论：检索得到28篇全文文章。所选研究确定的妇女B12缺乏症患病率从0.6%到45.5%不等。缺乏B12与女性患抑郁症/产后抑郁症、乳腺癌、复发性流产、妊娠期糖尿病、胰岛素抵抗和肥胖的风险有关。有必要监测和纠正妇女B12缺乏症，以防止并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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From Micro to Macro: Understanding the Far-Reaching Consequences of B12 Deficiency on Women's Health.

Background: Vitamin B12 (B12), playing the role of a coenzyme in one-carbon metabolism, is an important vitamin necessary for human health.

Objectives: To systematically review evidence to identify the complications of B12 deficiency among women.

Methods: We conducted a systematic search of quantitative studies on disorders associated with B12 deficiency among women, published in English in the last 25 years (1999-2024), using electronic databases such as Scopus, Web of science, CINAHL, PubMed, and Medline.

Conclusion: The search produced 28 full-text articles. B12 deficiency prevalence among women identified by the selected studies ranges from 0.6% to 45.5%. The deficiency of B12 is connected with the risk for depression/post-partum depression, breast cancer, recurrent pregnancy loss, gestational diabetes mellitus, insulin resistance, and obesity among women. It is necessary to monitor and correct the B12 deficiency among women in order to prevent complications.

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来源期刊

Public Health Nursing 医学-公共卫生、环境卫生与职业卫生

CiteScore

3.50

自引率

4.80%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Public Health Nursing publishes empirical research reports, program evaluations, and case reports focused on populations at risk across the lifespan. The journal also prints articles related to developments in practice, education of public health nurses, theory development, methodological innovations, legal, ethical, and public policy issues in public health, and the history of public health nursing throughout the world. While the primary readership of the Journal is North American, the journal is expanding its mission to address global public health concerns of interest to nurses.