急诊剖腹手术患者围手术期急诊剖腹手术路径:倾向评分匹配研究

IF 2.5 Q1 MEDICINE, GENERAL & INTERNAL Annals of the Academy of Medicine, Singapore Pub Date : 2024-12-26 DOI:10.47102/annals-acadmedsg.2024311
Joel Wen Liang Lau, Janardhan Baliga, Faheem Khan, Ying Xin Teo, Jonathan Ming Jie Yeo, Vincent Zhiwei Yeow, Christine Xia Wu, Stephanie Teo, Tracy Jia Hui Goh, Philip Iau
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引用次数: 0

摘要

简介:急诊剖腹手术(EL)的发病率和死亡率高,通常超过10%。本研究评估了急诊剖腹手术审计(EMLA)跨学科围手术期途径对单个中心患者预后、住院费用和住院时间(LOS)的影响。方法:于2020年8月至2023年7月进行前瞻性队列研究。干预小组包括专业临床医生、医院管理人员和一个院内质量改进小组。将接受EL治疗的患者分为干预前对照组(n=136)和干预后组(n=293),实施8项捆绑治疗。倾向评分采用1:1匹配方法,以减少混淆和选择偏差。检查的主要结果是LOS、住院费用和手术发病率,而次要结果包括30天死亡率和对干预方案的依从性。结果:EMLA围手术期护理包的使用导致手术并发症显著减少(34.8%至20.6%,PP=0.03),住院费用降低(40,160新元至30,948新元,P=0.04)。对关键干预措施的依从性也有所改善。然而,30天死亡率没有差异。结论:本研究为外科单位如何实施全身围手术期改变以改善急诊剖腹手术患者的预后提供了见解。
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Perioperative emergency laparotomy pathway for patients undergoing emergency laparotomy: A propensity score matched study.

Introduction: Emergency laparotomy (EL) is associated with high morbidity and mortality, often exceeding 10%. This study evaluated the impact of the EMergency Laparotomy Audit (EMLA) interdisciplinary perioperative pathway on patient outcomes, hospital costs and length of stay (LOS) within a single centre.

Method: A prospective cohort study was conducted from August 2020 to July 2023. The intervention team included specialist clinicians, hospital administrators and an in-hospital quality improvement team. Patients who underwent EL were divided into a pre-intervention control group (n=136) and a post-intervention group (n=293), and an 8-item bundle was implemented. Propensity scoring with a 1:1 matching method was utilised to reduce confounding and selection bias. The primary outcomes examined were LOS, hospitalis-ation costs and surgical morbidity, while secondary outcomes included 30-day mortality and adherence to the intervention protocol.

Results: The utilisation of the EMLA perioperative care bundle led to a significant reduction in surgical complications (34.8% to 20.6%, P<0.01), a decrease in LOS by 3.3 days (15.4 to 12.1 days, P=0.03) and lower hospitalisation costs (SGD 40,160 to 30,948, P=0.04). Compliance with key interventions also showed improvement. However, there was no difference in 30-day mortality.

Conclusion: This study offers insights on how surgical units can implement systemic perioperative changes to improve outcomes for patients undergoing emergency laparotomy.

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