1型糖尿病患者和非1型糖尿病患者的饮食失调:全国人群队列的发病率和治疗

IF 8.4 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetologia Pub Date : 2025-01-04 DOI:10.1007/s00125-024-06346-7
Leon Hirvelä, Jari Haukka, Anna Keski-Rahkonen, Pyry N. Sipilä
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引用次数: 0

摘要

目的/假设饮食失调在1型糖尿病中占比过高,且与并发症风险增加有关,但目前尚不清楚1型糖尿病是否会影响饮食失调的治疗。我们评估了全国1型糖尿病患者和无糖尿病对照人群中饮食失调的发病率和治疗情况。方法本研究纳入了1998-2010年间诊断为1型糖尿病的11055名30岁患者,以及11055名年龄、性别和医院区相匹配的无糖尿病对照患者。我们使用泊松回归从医院记录中确定饮食失调的发生率。通过精神药物的新处方和饮食失调的住院治疗来评估饮食失调的治疗。结果在平均13.1年的随访中,1型糖尿病患者中有175例饮食失调事件,对照组中有75例(调整后发病率比2.35;95% ci 1.80, 3.09)。在患有和不患有1型糖尿病的饮食失调患者中,精神药物的处方相似。然而,1型糖尿病患者因饮食失调而接受门诊治疗的次数少于非糖尿病患者(平均每年3.32次vs 5.33次)[调整差1.24;95% ci 0.39, 2.08])。结论/解释1型糖尿病患者比无糖尿病的同龄人更容易被诊断为饮食失调。然而,他们接受较少门诊治疗的饮食失调,尽管他们的主要不良健康结果的风险更大。这些发现强调了对1型糖尿病患者进行有针对性的饮食失调治疗的必要性。图形抽象
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Eating disorders among people with and without type 1 diabetes: incidence and treatment in a nationwide population-based cohort

Aims/hypothesis

Eating disorders are over-represented in type 1 diabetes and are associated with an increased risk of complications, but it is unclear whether type 1 diabetes affects the treatment of eating disorders. We assessed incidence and treatment of eating disorders in a nationwide sample of individuals with type 1 diabetes and diabetes-free control individuals.

Methods

Our study comprised 11,055 individuals aged <30 who had been diagnosed with type 1 diabetes in 1998–2010, and 11,055 diabetes-free control individuals matched for age, sex and hospital district. We ascertained incidence of eating disorders from hospital records using Poisson regression. Eating disorder treatment was assessed by new prescriptions for psychotropic medications and hospital treatment for eating disorders.

Results

During a mean follow-up of 13.1 years, there were 175 incident cases of eating disorders among individuals with type 1 diabetes and 75 among the control individuals (adjusted incidence rate ratio 2.35; 95% CI 1.80, 3.09). The prescription of psychotropic medications was similar among eating disorder patients with and without type 1 diabetes. However, those with type 1 diabetes received outpatient hospital treatment for their eating disorder less often than those without diabetes (mean 3.32 vs 5.33 outpatient care visits per year [adjusted difference 1.24; 95% CI 0.39, 2.08]).

Conclusions/interpretation

People with type 1 diabetes are more likely to be diagnosed with eating disorders than their diabetes-free peers. However, they receive less outpatient hospital treatment for their eating disorders despite their greater risk for major adverse health outcomes. These findings emphasise the need for targeted eating disorder treatment for people with type 1 diabetes.

Graphical Abstract

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来源期刊
Diabetologia
Diabetologia 医学-内分泌学与代谢
CiteScore
18.10
自引率
2.40%
发文量
193
审稿时长
1 months
期刊介绍: Diabetologia, the authoritative journal dedicated to diabetes research, holds high visibility through society membership, libraries, and social media. As the official journal of the European Association for the Study of Diabetes, it is ranked in the top quartile of the 2019 JCR Impact Factors in the Endocrinology & Metabolism category. The journal boasts dedicated and expert editorial teams committed to supporting authors throughout the peer review process.
期刊最新文献
Correction: A whole-food, plant-based intensive lifestyle intervention improves glycaemic control and reduces medications in individuals with type 2 diabetes: a randomised controlled trial. Correction: Applying technologies to simplify strategies for exercise in type 1 diabetes. Autoimmune diseases and the risk and prognosis of latent autoimmune diabetes in adults. Characterising impaired awareness of hypoglycaemia and associated risks through HypoA-Q: findings from a T1D Exchange cohort. Diabetes knowledge and behaviour: a cross-sectional study of Jordanian adults.
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