水凝胶在宫内粘连治疗中的应用。

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY Current pharmaceutical design Pub Date : 2025-01-01 DOI:10.2174/0113816128348746241030110806
Yasamin Rajabloo, Abdulridha Mohammed Al-Asady, Hanieh Akbarzadeh, Amir Avan, Majid Khazaei, Mikhail Ryzhikov, Seyed Mahdi Hassanian
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引用次数: 0

摘要

子宫内膜粘连(IUA)是导致不孕和流产的重要原因,通常由子宫内膜外伤引起。虽然宫腔镜粘连溶解是主要的治疗方法,但水凝胶作为抗粘连屏障和药物输送系统的使用正在获得改善患者预后的吸引力。本文旨在探讨不同类型的水凝胶及其在组织修复中的作用,以及与干细胞治疗的结合。近年来,生物材料支架在预防粘连复发和促进子宫内膜再生方面取得了很大的进展。这些新兴疗法为提高IUA管理中传统疗法的疗效提供了有希望的途径。
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The Application of Hydrogels in the Treatment of Intrauterine Adhesions.

Intrauterine Adhesions (IUA) are a significant cause of infertility and miscarriage, often resulting from trauma to the endometrium. While hysteroscopic adhesiolysis is the primary treatment, the use of hydrogels as anti-adhesion barriers and drug delivery systems is gaining traction for improving patient outcomes. This review aims to explore various hydrogel types, their role in tissue repair, and the integration of stem cell therapy. Recent advancements in biomaterial scaffolds have demonstrated potential in preventing adhesion recurrence and promoting endometrial regeneration. These emerging treatments provide promising avenues for enhancing the efficacy of traditional therapies in IUA management.

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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
302
审稿时长
2 months
期刊介绍: Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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